ABSTRACT
No abstract available.
Subject(s)
Humans , Infant , Exanthema , Leukemia , Leukemia, Myeloid, AcuteABSTRACT
Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Subject(s)
Humans , Dermatitis , Dermatitis, Perioral , Metronidazole , Mouth , Nose , TacrolimusABSTRACT
Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Subject(s)
Humans , Dermatitis , Dermatitis, Perioral , Metronidazole , Mouth , Nose , TacrolimusABSTRACT
BACKGROUND: Dermoscopy has been suggested as a useful tool for diagnosing various skin diseases. Recently, the possibility of using dermoscopy to predict the response to treatment has emerged. OBJECTIVE: The purpose of this study was to determine whether dermoscopic findings corresponded to clinical acne scar types. This study also aimed to discover which dermoscopic findings predict the response to acne scar treatment. METHODS: The dermoscopic findings of 39 participants undergoing atrophic acne scar treatment with fractional photothermolysis were evaluated. Patients were divided into two groups according to the duration of acne scar persistence. RESULTS: Patients with a relatively short duration of acne scar persistence usually achieved better treatment outcomes. Dermoscopic findings showed no obvious differences according to clinical acne scar type. But high hair follicle density can be considered a predictive factor of treatment effects. CONCLUSION: Our study indicated that acne scar improvements can be predicted by dermoscopically observing hair follicle density.
Subject(s)
Humans , Acne Vulgaris , Cicatrix , Dermoscopy , Hair Follicle , Pilot Projects , Skin DiseasesABSTRACT
BACKGROUND: Atrophic acne scars have been treated using various modalities. The CROSS (Chemical Reconstruction of Skin Scars) technique using 100% TCA has the advantage of reconstructing acne scars by focusing on dermal thickening and collagen production. However, the phenol CROSS technique is not widely used for acne scarring. OBJECTIVE: The purpose of this study was to evaluate the clinical effectiveness and safety of 100% TCA CROSS and phenol CROSS in the treatment of facial atrophic acne scars. METHODS: Twenty-four participants were randomly and equally divided into 2 groups: group 1 received 2 sessions (8 weeks apart) of 100% TCA CROSS, while group 2 received 2 sessions (8 weeks apart) of phenol CROSS. The severity of atrophic acne scarring and treatment efficacies were evaluated by standardized photography, patient satisfaction, physician global assessment, and the ECCA grading scale. Side effects were assessed at the 8- and 20-week visits. RESULTS: At the 0-, 8-, and 20-week visits, both groups showed an acceptable improvement in patient satisfaction and physician global assessment. ECCA grading scale scores improved by a mean of 22.2% (p<0.05) in group 1 and 19.1% (p<0.05) in group 2. The between-group difference in the degree of ECCA score improvement was not statistically significant (p=0.392). Complications such as pain, crust, postcrust erythema, postcrust dryness, and postinflammatory hyperpigmentation were observed in both treatment groups. However, no severe side effects occurred in either group. CONCLUSION: Both 100% TCA CROSS and phenol CROSS are effective treatment modalities for atrophic acne scarring without significant side effects.
Subject(s)
Acne Vulgaris , Cicatrix , Collagen , Erythema , Hyperpigmentation , Patient Satisfaction , Phenol , Photography , Skin , Trichloroacetic AcidABSTRACT
Rowell's syndrome is a rare entity consisting of lupus erythematosus with associated erythema multiforme-like lesions and characteristic immunological findings, and it was first described by Rowell et al. in 1963. Because of the clinical similarities between subacute cutaneous lupus erythematosus and Rowell's syndrome, it is difficult to clinically distinguish between the annular-polycyclic type of subacute cutaneous lupus erythematosus and Rowell's syndrome. We report a case of 18-year-old woman with systemic lupus erythematosus who presented erythema multiforme-like eruptions on both thighs. Simultaneously, she developed urticarial-like rashes on her trunk consistent with atypical skin lesion of lupus erythematosus. She also developed a positive antinuclear antibody with speckled pattern and positive anti-Ro antibody.
Subject(s)
Female , Humans , Antibodies, Antinuclear , Erythema , Erythema Multiforme , Exanthema , Lupus Erythematosus, Cutaneous , Lupus Erythematosus, Systemic , Skin , ThighABSTRACT
We report a case of pityriasis versicolor atrophicans in a 20-year-old woman who presented with chronic multiple brownish atrophic macules and patches on chest and back. The lesions had developed six years ago and the patient had used topical medication including steroid ointments for the last two years prior to visiting our clinic. KOH examination was positive, so skin biopsy was performed and the diagnosis of pityriasis versicolor atrophicans was made. Since our patient had applied topical steroids for some time, it was difficult to rule out steroid-induced atrophy in a common tinea versicolor. Also, differential diagnosis was performed with respect to other skin diseases manifesting with cutaneous atrophy including anetoderma.
Subject(s)
Female , Humans , Young Adult , Anetoderma , Atrophy , Biopsy , Diagnosis, Differential , Ointments , Pityriasis , Skin , Skin Diseases , Steroids , Thorax , Tinea VersicolorABSTRACT
Kerion celsi is an inflammatory dermatophytosis of the scalp which is characterized by an acute suppurative process caused mainly by zoophilic dermatophytes. Systemic corticosteroid can be added to systemic antifungal treatment for reducing scarring alopecia, but focal cicatricial changes are unavoidable in a severe case. We report a case of kerion celsi caused by T. mentagrophytes, zoophilic dermatophyte, in a 7-year-old girl. This patient had localized painful erythematous crusted plaques with multiple inflammatory pustules on the scalp. Although she was initially treated with antifungal agent and systemic corticosteroid, focal scarring alopecia occurred eventually. Eventually, the cicatricial change was corrected surgically after two and a half years in spite of timely and appropriate treatment.
