ABSTRACT
A benign teratoma of the fallopian tube occurred in association with a tubal pregnancy. This rare finding should be considered when two masses are present within a fallopian tube.
Subject(s)
Dermoid Cyst/complications , Fallopian Tube Neoplasms/complications , Pregnancy, Tubal/complications , Teratoma/complications , Adult , Dermoid Cyst/pathology , Fallopian Tube Neoplasms/pathology , Female , Humans , Pregnancy , Pregnancy, Tubal/pathology , Teratoma/pathologyABSTRACT
Fifteen rabbits were used to assess peritoneal healing and adhesion formation after suturing and stapling peritoneal edges or excising, cauterizing and abrading areas of peritoneum. Two weeks after peritoneal injury, the amount of adhesions formation was noted. Resection of peritoneal tissue with natural rehealing was preferable to reapproximation of free peritoneal edges with either staples or sutures.
Subject(s)
Peritoneal Diseases/prevention & control , Peritoneum/surgery , Postoperative Complications/prevention & control , Animals , Electrocoagulation , Female , Peritoneal Diseases/etiology , Postoperative Complications/etiology , Rabbits , Surgical Staplers , Suture Techniques , Tissue Adhesions/etiology , Tissue Adhesions/prevention & control , Wound HealingABSTRACT
Tolmetin, a nonsteroidal anti-inflammatory drug, is rapidly absorbed (10 to 20 min) and rapidly excreted (T1/2 congruent to 60 min) and shows a linear dose-plasma level response in the therapeutic dose range. Tolmetin does not affect its own metabolism on chronic administration. Tolmetin is displaced, in vitro, from plasma proteins by salicylic acid. This effect is reflected in minor changes in plasma levels and pharmacokinetic parameters when aspirin and tolmetin are coadministered.
Subject(s)
Pyrroles/metabolism , Tolmetin/metabolism , Aspirin/blood , Biological Availability , Blood Proteins/metabolism , Dose-Response Relationship, Drug , Half-Life , Humans , Kinetics , Male , Protein Binding , Salicylates/blood , Tablets , Tolmetin/administration & dosage , Tolmetin/bloodABSTRACT
In a clinical study of the new nonsteroidal anti-inflammatory drug tolmetin, the urines of 5 patients reacted positively when tested for protein by the standard sulfosalicylic acid method. Pseudoproteinuria, due to the precipitation by acid of the major metabolite of tolmetin, was suspected. The urines were subsequently tested for protein by the following alternate methods: solubility of acid precipitate test, heat coagulation test, Upjohn modification of the sulfosalicylic acid test, biuret test, Albustix, and electrophoresis. All were negative for protein. These results confirmed that the reactions with the sulfosalicylic acid test did not indicate true proteinuria but pseudoproteinuria. It is suggested that patients who receive tolmetin be tested for proteinuria by methods other than those involving acid precipitation.
