ABSTRACT
The objective of this study was to investigate the risk factors and diagnosis measure of COVID-19-associated pulmonary aspergillosis (CAPA). This study included 201 COVID-19 patients from December 1, 2022, to January 31, 2023; 7 (3.5%) were diagnosed with CAPA. The main risk factors were age, MV, ICU admission and COPD, and the presence of comorbidities such as ARDS and hypoproteinemia in COVID-19 patients, more susceptible to Aspergillus infection. In addition to specimen culture in the lower respiratory tract, the 1,3-ß-D-glucan antigen test can serve as an important screening indicator for early CAPA diagnosis in non-granulocytopenia patients.
Subject(s)
COVID-19 , Coinfection , Pulmonary Aspergillosis , SARS-CoV-2 , Humans , COVID-19/complications , Coinfection/microbiology , Male , Middle Aged , Female , Pulmonary Aspergillosis/complications , Pulmonary Aspergillosis/epidemiology , Aged , Risk Factors , Adult , Retrospective Studies , Comorbidity , Aged, 80 and overABSTRACT
Burkholderia pyrrocinia strain JK-SH007 isolated from poplar stems plays a highly significant role in the growth promotion and the biocontrol of poplar canker during colonization in poplar. In this research, the ideal reference gene was filtered and determined for the transcript normalization. Additionally, the expression of pyrG under all four conditions was relatively stable in B. pyrrocinia JK-SH007.
