1.
Org Lett
; 21(13): 5225-5228, 2019 07 05.
Article
in English
| MEDLINE
| ID: mdl-31247749
ABSTRACT
An efficient construction of 1-phenylchromeno[3,4- b]pyrrol-4(3 H)-one via coupling of 1-styrylpyrrolidine and 4-chloro-3-nitrocoumarin as a key step is reported. This reaction is further applied to the total synthesis of the natural product ningalin B in five linear steps with an overall yield of 41.5% and a pyrrolocoumarin-based electrochromic switch.