ABSTRACT
A new triterpenoid, namely 3ß-hydroxy-13ß,28-epoxyolean-11-enyl trans-caffeate (1), was isolated from the EtOAc extract from Ixeris chinensis Nakai. The structures of 1 were elucidated by spectroscopic methods, including UV, IR, HR-ESI-MS and extensive 1D and 2D NMR techniques.
Subject(s)
Asteraceae/chemistry , Magnetic Resonance Spectroscopy , Triterpenes/chemistry , Acetates , Molecular Structure , Plant Extracts/chemistry , Spectrum Analysis , Triterpenes/isolation & purificationABSTRACT
Two new compounds, named as sacric acid A (1) and sacric acid B (2), were isolated from the EtOAc extract of Artemisia sacrorum Ledeb. This is the first report on the structure elucidation of these compounds based on UV, IR, and extensive ID and 2D NMR spectroscopic, and ESI-MS techniques.
Subject(s)
Artemisia/chemistry , Caffeic Acids/isolation & purification , Caffeic Acids/chemistry , Molecular StructureABSTRACT
The present study was designed to isolate and characterize the analgesic compounds of Artemisa sacrorum Ledeb. The EtOAc crude extracts from the aerial parts of Artemisa sacrorum Ledeb were separated by chromatography and the structures of new compounds were elucidated based on spectral analyses. Analgesic activities of the isolated compounds were assessed in rats with hot plate test and paw pressure assay. Two new flavone C-glycosides, named as Sacroroside A and B (Compounds 1 and 2) were isolated from the EtOAc crude extract of the aerial parts ofArtemisa sacrorum Ledeb. They showed significant analgesic effects. In conclusion, Compounds 1 and 2 are new natural products, which show significant analgesic effects in a dose-dependent manner.
Subject(s)
Analgesics/therapeutic use , Artemisia/chemistry , Disaccharides/therapeutic use , Flavanones/therapeutic use , Flavones/therapeutic use , Pain/drug therapy , Phytotherapy , Plant Extracts/therapeutic use , Analgesics/chemistry , Analgesics/isolation & purification , Analgesics/pharmacology , Animals , Disaccharides/chemistry , Disaccharides/isolation & purification , Disaccharides/pharmacology , Flavanones/chemistry , Flavanones/isolation & purification , Flavanones/pharmacology , Flavones/chemistry , Flavones/isolation & purification , Flavones/pharmacology , Hot Temperature , Male , Molecular Structure , Plant Components, Aerial , Plant Extracts/chemistry , Plant Extracts/pharmacology , Pressure , Rats, WistarABSTRACT
OBJECTIVE: To study the chemical constituents of the ethyl acetate extract from Panzeria alaschanica. METHODS: The chemical constituents of ethyl acetate extract from Panzeria alaschanica were isolated and purified by silica gel. Their structures were i- dentified by means of spectra. RESULTS: Nine compounds were obtained and identified as 7-Methoxy coumarin (1), Isorhamnetin (2), Caf- feic acid (3), 5-Hydroxy-7,3',4'-trimethoxyflavone (4), 5-Hydroxy-7,4'-dimethoxyflavone (5),Kaempferol (6), Isorhamnetin-3-O-ß-D- glucoside (7) Kaempferol-3-O-ß-D-glucoside (8), and Isorhamnetin-7-O-ß-D-glucuronyl-(1-->6)-O-α-L-rhamnoside (9). CONCLUSION: Compounds 1-4,6,7 and 9 are isolated from this plant for the first time.
Subject(s)
Phytochemicals/analysis , Plant Extracts/chemistry , Plants, Medicinal/chemistry , Glucosides , Kaempferols , Monosaccharides , Quercetin/analogs & derivativesABSTRACT
A biflavonoid glycoside with a new carbon skeleton, named carinoside A, was isolated from the n-BuOH crude extract of the whole plant of Lomatogonium carinthiacum (Wulf) Reichb. The structure of the new compound was elucidated by using spectroscopic methods, including UV, IR, HR-ESI-MS and extensive 1D and 2D NMR techniques.
Subject(s)
Biflavonoids/isolation & purification , Drugs, Chinese Herbal/isolation & purification , Gentianaceae/chemistry , Glycosides/isolation & purification , Biflavonoids/chemistry , Drugs, Chinese Herbal/chemistry , Glycosides/chemistry , Molecular Structure , Nuclear Magnetic Resonance, BiomolecularABSTRACT
The petroleum ether (PE) extract from Ixeris chinensis was submitted to chromatographic separation. A new sesquiterpene, namely 14-noreudesma-3-hydroxy-3-en-2,9-dione, was isolated from the PE extract. The structures of the sesquiterpene was elucidated by using spectroscopic methods, including UV, IR, HR-ESI-MS and extensive 1D and 2D NMR techniques.
