ABSTRACT
We report an ionogel with thermo-switchable conductivity and high processability based on physical self-assembly of poly(styrene-b-ethylene oxide-b-styrene) (PS-PEO-PS) in mixed ionic liquids composed of thermo-responsive 1,3-dimethylimidazolium bis(trifluoromethanesulfonyl)imide and polymerizable 1-(4-vinylbenzyl)-3-butylimidazolium bis(trifluoromethylsulfonyl)imide, and subsequent chemical crosslinking of the polymerizable component.
ABSTRACT
Location data have great value for facility location selection. Due to the privacy issues of both location data and user identities, a location service provider can not hand over the private location data to a business or a third party for analysis or reveal the location data for jointly running data analysis with a business. In this paper, we propose a newly constructed PSI filter that can help the two parties privately find the data corresponding to the items in the intersection without any computations and, subsequently, we give the PSI filter generation protocol. We utilize it to construct three types of aggregate protocols for facility location selection with confidentiality. Then we propose a ciphertext matrix compressing method, making one block of cipher contain lots of plaintext data while keeping the homomorphic property valid. This method can efficiently further reduce the computation/communication cost of the query process-the improved query protocol utilizing the ciphertext matrix compressing method is given followed. We show the correctness and privacy of the proposed query protocols. The theoretical analysis of computation/communication overhead shows that our proposed query protocols are efficient both in computation and communication and the experimental results of the efficiency tests show the practicality of the protocols.
Subject(s)
Computer Security , Confidentiality , PrivacyABSTRACT
The purpose of this study was to analyze ß-catenin and matrix metalloproteinase-2 (MMP-2) expression in non-small cell lung cancer (NSCLC) and to investigate the association between their expression and clinicopathologic characteristics of NSCLC patients. Immunohistochemistry was performed to examine ß-catenin and MMP-2 protein expression in 39 resected NSCLC samples and 8 adjacent normal lung tissues. Statistical analysis with SPSS13.0 software was performed to investigate the association between ß-catenin and MMP-2 expression and clinicopathologic features of the patients. Expression of cytosolic ß-catenin in NSCLC tissue was significantly higher than that in normal tissues (P < 0.001). In addition, cytosolic protein expression of ß-catenin in lung squamous cell carcinoma was significantly elevated compared to that in lung adenocarcinoma (P = 0.02). However, cell membrane protein expression of ß-catenin in squamous cell carcinoma was lower than that in adenocarcinoma (P = 0.041). Cytosolic MMP-2 protein expression in NSCLC samples was significantly higher than that in normal tissues (P = 0.002). MMP-2 expression in N (1-2) NSCLC patients was significantly increased relative to N (0) patients (P = 0.019). However, statistical analysis showed no correlation between ß-catenin and MMP-2 expression in NSCLC samples. Collectively, our results show that cytosolic protein expression of ß-catenin in NSCLC samples is increased relative to normal lung tissues. Also, expression of ß-catenin is significantly elevated in squamous cell carcinoma compared to that in lung adenocarcinoma subtypes. Additionally, MMP-2 expression in N (1-2) NSCLC tissues is higher than that in N (0) lung tissue. There is no correlation between ß-catenin and MMP-2 expression in NSCLC, and our study suggests that evaluation of ß-catenin and MMP-2 expression may have potential in diagnosis and progression in patients with NSCLC.
