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J Biomed Nanotechnol ; 17(8): 1525-1534, 2021 Aug 01.
Article in English | MEDLINE | ID: mdl-34544530

ABSTRACT

The development of science and technology has deepened people's understanding of cancer, changing the management of malignant tumors in the medical field. Given the common precancerous characteristics of colorectal cancer (CRC), researchers studied early CRC screening. The complexity of traditional diagnostics forced medical staff to speed up CRC innovation early screening methods. Here, we prepared nano-colloidal gold raw materials with different particle sizes (15 and 30 nm) and observed the morphological characteristics and properties of the materials. Simultaneously, the nanocolloidal gold double antibody sandwich kit was designed through the optimum pH value and protein content screening experiment. The results of clinical enteroscopy confirmed the important guiding significance of the equipment in early CRC screening.


Subject(s)
Colorectal Neoplasms , Occult Blood , Chromatography, Affinity , Colorectal Neoplasms/diagnosis , Early Detection of Cancer , Gold Colloid , Humans
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