Type 2 diabetes mellitus increases the risk of circumcision among men aged between 30 and 69 years using a nationwide population-based dataset in Taiwan: a five-year follow-up study.

BACKGROUND: Diabetes is an important factor in the development of penile inflammation. We studied whether type 2 diabetes (DM), with/without hypertension and hyperlipidemia increased the risk of circumcision among men aged between 30 and 69 using a population-based dataset in Taiwan during a 5-year follow-up period. METHODS: The research data in this study were obtained from Taiwan's National Health Insurance Research Database between 1997 and 2010. We identified 23,197 patients who had a new diagnosis of DM and randomly matched 115,985 subjects as controls. We observed whether circumcision was the treatment after a new DM diagnosis. The initial step involved analyzing the data using Poisson regression analysis. To address potential confounding factors, this study employed propensity score matching based on three variables. Additionally, a Cox regression with a Gamma frailty was utilized to compare outcomes between different groups. RESULTS: Poisson regression analysis showed that DM (RR = 1.75, 95CI = 0.10 ~ 1.22), but not hypertension (RR = 1.14, 95CI=-0.44 ~ 0.70), hyperlipidemia (RR = 0.94, 95CI=-0.66 ~ 0.53), or age (RR = 0.83, 95CI=-0.43 ~ 0.62), had an impact on circumcision treatment. Cox regression with a frailty model found that DM was a risk factor associated with circumcision (HR = 2.31, 95% CI = 1.74 ~ 3.06, p-value < 0.01), whereas no significant difference was noted between circumcision and hypertension (HR = 1.10, 95% CI = 0.80 ~ 1.51), hyperlipidemia (HR = 1.05, 95% CI = 0.79 ~ 1.40), or age (HR = 1.00, 95% CI = 0.99 ~ 1.02). CONCLUSIONS: Type 2 diabetes mellitus, but not hypertension, hyperlipidemia or age increases the risk of circumcision in men aged between 30 and 69 years.

Effect of different mixing modes on the abundance of Microcystis in Lake Taihu under green light.

Light and hydrodynamic force are important physical factors affecting growth of Microcystis. The most recent study found that green light has good effect in inhibiting growth of Microcystis. To understand the effect of mixing modes on Microcystis under the green light, we investigated the effects of continuous mixing and intermittent mixing on the abundance of Microcystis in Taihu Lake under field conditions. The study results found that abundance of Microcystis in control, intermittent mixing group, and continuous mixing group decreased 76.62%, 40.36%, and 95.18% on day 7 compared with that on day 1 in this experiment. At the end of the experiment, abundance percentages of diatoms and green algae to total phytoplankton abundance were 1.57% and 0.48% in control, 2.32% and 0.67% in intermittent mixing group, and 22.47% and 20.27% in continuous mixing group. The results indicated that continuous mixing favored the removal of Microcystis under green light conditions and was helpful for the growth of green algae and diatoms. The results provide a new approach for the control of Microcystis blooms.

Effects of zinc and iron on the abundance of Microcystis in Lake Taihu under green light and turbulence conditions.

Trace element is one of the important factors affecting the growth of Microcystis. The effects of zinc (0.4 mg/L) and iron (2 mg/L) on the abundance of Microcystis in Lake Taihu were investigated under continuous turbulence and green light conditions in a microcosm experiment. The study results showed that the abundance of Microcystis in the zinc treatment and the iron treatment group was 8.30% and 214% of that in the control group at the end of the experiment, respectively. The proportion of Cyanobacteria in the total phytoplankton biomass in the control, iron treatment, and zinc treatment group decreased from 99.99% at the beginning of the experiment to 13%, 18%, and 1% at the end of the experiment, respectively. At the end of the microcosm experiment, the phytoplankton community was dominated by Bacillariophyta in the control group, accounting for 63%, but it was dominated by Chlorophyta in the zinc treatment and the iron treatment group, accounting for 89% and 42%, respectively. The study results showed that under green light and turbulence, 0.4 mg/L zinc remarkably decreased the abundance of Microcystis, but 2 mg/L iron effectively increased the number of Microcystis and other algae. This research results provided a new idea for controlling Microcystis blooms.