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1.
Sensors (Basel) ; 23(4)2023 Feb 07.
Article in English | MEDLINE | ID: mdl-36850473

ABSTRACT

Dense mapping is an important part of mobile robot navigation and environmental understanding. Aiming to address the problem that Dense Surfel Mapping relies on the input of a common-view relationship, we propose a local map extraction strategy based on spatiotemporal consistency. The local map is extracted through the inter-frame pose observability and temporal continuity. To reduce the blurring of map fusion caused by the different viewing angles, a normal constraint is added to the map fusion and weight initialization. To achieve continuous and stable time efficiency, we dynamically adjust the parameters of superpixel extraction. The experimental results on the ICL-NUIM and KITTI datasets show that the partial reconstruction accuracy is improved by approximately 27-43%. In addition, the system achieves a greater than 15 Hz real-time performance using only CPU computation, which is improved by approximately 13%.

2.
Animals (Basel) ; 13(3)2023 Jan 31.
Article in English | MEDLINE | ID: mdl-36766375

ABSTRACT

The aim of this trial was to assess whether the supplementation of vitamin E (VE) in high-concentrate diets could improve the fermentation and blood metabolism in the rumen of dairy cows, thereby modulating the degree of the subacute ruminal acidosis (SARA) response and improving the performance. Seven Holstein cows (four fitted with ruminal cannulas) were fed three diets (total mixed rations) during three successive periods (each lasted for 18 d): (1) the control diet (CON); (2) a high-grain (HG) diet, which was the control diet supplied with a 15% finely ground wheat diet (FGW); and (3) a high-VE diet (HGE), which was the control diet provided with a 15% FGW and 12,000 IU of VE/head per day. The results indicated that VE was able to alleviate the reduction in the dry matter intake (DMI) and milk fat yield in cows caused by HG diets. The supplementation of VE significantly reduced the levels of lipopolysaccharide (LPS), histamine (HIS), and the total volatile fatty acid (TVFA) in the rumen. The supplementation of VE observably increased the antioxidant capacity of the milk and plasma. In addition, VE markedly reduced the plasma levels of endotoxin, HIS, and pro-inflammatory factors. The supplementation of VE significantly enriched the differential metabolites of the purine metabolism, cysteine, methionine metabolism, and ABC transporter synthesis pathway in the serum. The supplementation of VE also significantly increased the relative abundance of Succiniclasticum and decreased the relative abundance of Treponema, thus reducing the production of TVFA in the rumen. In conclusion, considering that the cows in this trial had high ketone levels (BHBA > 2.3 mmol/L), we found that VE could improve the rumen fermentation and blood metabolism by modulating the relative abundance of rumen microorganisms, thereby mitigating a range of adverse effects caused by SARA.

3.
Nan Fang Yi Ke Da Xue Xue Bao ; 29(2): 236-8, 2009 Feb.
Article in Chinese | MEDLINE | ID: mdl-19246287

ABSTRACT

UNLABELLED: To evaluate the detection rate of myocardial bridging by 64-slice spiral CT coronary angiography. METHODS: The data of 3011 patients with suspected coronary artery disease undergoing 64-slice spiral CT coronary angiography were collected and analyzed retrospectively. RESULTS: A total of 174 cases (5.8%) with myocardial bridging were detected by 64-slice spiral CT coronary angiography, among which 168 (96.6%) had single foci of involvement and 6 (3.4%) had were multiple foci. Involvement of the left anterior descending coronary artery (LAD) was detected in 167 out of the 174 cases (96.0%). The length of the myocardial bridge varied between 5 and 120 mm (mean of 30.5 mm), and the depth of the tunneled artery ranged between 1.3 and 2.8 mm (mean 2.3 mm). Seventy-nine of the cases (45.4%) had uncomplicated myocardial bridging and 95 (54.6%) had myocardial bridging complicated by coronary atherosclerosis. CONCLUSION: Multi-slice spiral CT coronary angiography is a reliable and noninvasive modality for diagnosis of myocardial bridging to allow direct measurement of the length and depth of the myocardial bridge and detection of concurrent coronary and cardiac lesions.


Subject(s)
Coronary Angiography/methods , Coronary Artery Disease/diagnostic imaging , Myocardial Bridging/diagnostic imaging , Tomography, Spiral Computed , Adult , Aged , Aged, 80 and over , China/epidemiology , Coronary Artery Disease/complications , Female , Humans , Male , Middle Aged , Myocardial Bridging/complications , Myocardial Bridging/epidemiology , Retrospective Studies , Tomography, Spiral Computed/methods
4.
Zhongguo Zhong Yao Za Zhi ; 28(10): 964-6, 2003 Oct.
Article in Chinese | MEDLINE | ID: mdl-15620190

ABSTRACT

OBJECTIVE: To observe the protective effects of Cleistocalyx operculatus on lipid peroxidation in rat liver microsomes and on the trauma of PC12 cells induced by H2O2. METHOD: The mouse liver homogenate lipid peroxidation assay and PC12 Cell culture and Cell viability (MTT assay) were applied. RESULT: Cleistocalyx operculatus showed strong protective effects on lipid peroxidation in rat liver microsomes in a dose-dependent manner and exhibited potent protective effects on the trauma of PC12 cells induced by H2O2 (200 micromol x L(-1)) when the concentration reached 1.00 g x L(-1). CONCLUSION: Cleistocalyx operculatus may be used as antioxidant to prevent or delay the pathogenesis of neural cell diseases.


Subject(s)
Drugs, Chinese Herbal/pharmacology , Lipid Peroxidation/drug effects , Microsomes, Liver/metabolism , Myrtaceae , Neuroprotective Agents/pharmacology , Animals , Antioxidants/pharmacology , Cytoprotection/drug effects , Dose-Response Relationship, Drug , Drugs, Chinese Herbal/isolation & purification , Hydrogen Peroxide/antagonists & inhibitors , Hydrogen Peroxide/toxicity , Male , Mice , Myrtaceae/chemistry , PC12 Cells , Plants, Medicinal/chemistry , Rats
5.
Cancer ; 94(3): 803-13, 2002 Feb 01.
Article in English | MEDLINE | ID: mdl-11857316

ABSTRACT

BACKGROUND: Based on the cross-reactivity of the human carcinoma antigen, HCA, with epiglycanin, a mouse mammary carcinoma cell surface glycoprotein, HCA has been detected in the tissue and blood of patients with every type of epithelium-derived cancer tested. METHODS: Competitive binding assays utilized the following antiepiglycanin antibodies: a polyclonal rabbit antiserum (immunoglobulin [Ig] G and IgM) in a radioimmunoassay; mouse monoclonal antibodies (Ab-1, IgM) on immunoplates; anti-idiotypic (Ab-2) and anti-anti-idiotypic (Ab-3) monoclonal antibodies (both IgG) from spleen cells of C57BL mice immunized, respectively, with Ab-1 and Ab-2, and utilized on immunoplates. IgG and IgM antibodies were evaluated for their ability to detect HCA and to distinguish between the blood of patients with, or without, carcinomas. RESULTS: Assays with the rabbit antiserum distinguished plasmas of metastatic breast carcinoma patients from those of patients with benign breast disease with a sensitivity of approximately 93% (specificity 90%). Antiepiglycanin IgM monoclonal antibodies (i.e., AE3) showed high specificity and sensitivity (> 90%) with sera from advanced carcinoma patients when compared with normal sera. The IgG anti-anti-idiotypic (Ab-3) monoclonal antibodies (i.e., AF2), which bind the same epitope as Ab-1, appear to possess less nonspecific binding capacity, however, than the Ab-1 (IgM) antibodies. Anti-Ab-1 (i.e., C8F2) anti-idiotypic monoclonal antibodies, which bear an idiotope equivalent to the epitope present in epiglycanin and the HCA, demonstrated greater consistency as a standard calibrator and for coating wells than epiglycanin. CONCLUSIONS: The concentration of the HCA in the body fluids of patients with carcinomas may be accurately determined by competitive binding assays. It is suggested that the use of anti-idiotypic antibodies (IgG), rather than epiglycanin/HCA, and Ab-3 anti-anti-idiotypic antibodies (IgG), rather than Ab-1 (IgM), will improve the consistency, as well as the sensitivity and specificity, of the assay.


Subject(s)
Antibodies, Anti-Idiotypic/analysis , Antigens, Neoplasm/analysis , Antigens, Surface/analysis , Biomarkers, Tumor/analysis , Breast Neoplasms/immunology , Carcinoma/immunology , Immunoglobulin G/analysis , Immunoglobulin M/analysis , Integrins/analysis , Adult , Animals , Antibodies, Monoclonal , Antibodies, Neoplasm/analysis , Breast Neoplasms/pathology , Carcinoma/pathology , Female , Humans , Integrin alpha6beta4 , Mice , Rabbits , Radioimmunoassay , Sensitivity and Specificity
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