1.
J Org Chem
; 86(11): 7425-7438, 2021 06 04.
Article
in English
| MEDLINE
| ID: mdl-34008975
ABSTRACT
(Per)fluorinated substances represent an important compound class with regard to drug design and material chemistry. We found a mild, operationally simple, and inexpensive photocatalytic perfluoroalkenylation reaction giving tetrasubstituted, highly electron-deficient enals straight from aldehydes. This one-step reaction tolerates various functional groups and can be applied to a wide range of substrates giving the products in yields of 52-84%.