ABSTRACT
Laboratory classification of red cell disorders uses the red cell indices (MCV, MCH, MCHC, RDW) and information gleaned from microscopic evaluation of a blood film. Additional red cell information is now available using the H series of automated blood cell analysers (Ames Technicon Division of Bayer Diagnostics). This study involved the development of a discriminant rule which would differentiate between three causes of macrocytosis (vitamin B12/folate deficiency, alcohol excess/liver disease and a reticulocytosis) using the information available on Research Screen 1 and Report Screen 3 of the H*1 instrument (Report Screen 3 is a graphical display of the trimmed scattergram of red cell volume and red cell haemoglobin concentration and Research Screen 1 displays the associated numerical data). Three methods of analysis were assessed to define a suitable discriminant rule. The percentages of patients correctly classified by the three methods were: 92.1%, 82.0% and 89.2% for Methods 1, 2 and 3 respectively. Method 1 involved the application of quadratic discrimination to transformed variables and produced the best results. Although complex, it could easily be applied using the microprocessor capability of the average multiparameter haematology analyser.
Subject(s)
Anemia, Macrocytic/blood , Erythrocyte Indices , Erythrocytes, Abnormal/ultrastructure , Folic Acid Deficiency/diagnosis , Hemoglobins/analysis , Liver Diseases/diagnosis , Vitamin B 12 Deficiency/diagnosis , Alcoholism/blood , Alcoholism/complications , Anemia, Macrocytic/etiology , Diagnosis, Differential , Discriminant Analysis , Female , Folic Acid Deficiency/blood , Folic Acid Deficiency/complications , Humans , Liver Diseases/blood , Liver Diseases/complications , Male , Reference Values , Reticulocyte Count , Vitamin B 12 Deficiency/blood , Vitamin B 12 Deficiency/complicationsABSTRACT
There has been a century of theorizing that self-conceptions begin to develop early, heavily involve language, are important aspects of personality, and are much influenced by others' reactions. Nevertheless, no one has heretofore probed the empirical characteristics and antecedents of mothers' language that might be relevant to their 2 1/2-year-old children's acquisition of self-conceptions. In this research, such "maternal attributions" were located in video transcripts of 3 mother-child pairs, each interacting for 300 minutes (Study 1), and of 35 mother-child pairs, each interacting for 35 minutes (Study 2), all in a seminaturalistic setting. Study 2 replicated and extended results from Study 1 regarding (a) types of occasion for maternal attributions; and (b) the attributions' specificity/abstractness, vocabulary content, substantive referent, explicitness/implicitness, evaluative tone, and direction toward the whole child or an aspect of the child. Antecedent-consequent relationships were found between children's roles in occasioning attributions and the language specificity and evaluative tone of the attributions. Results are discussed in terms of the development of the self.
