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1.
Nanomaterials (Basel) ; 9(3)2019 Mar 04.
Article in English | MEDLINE | ID: mdl-30836594

ABSTRACT

The microscopic and semi-macroscopic mechanisms responsible for photoinduced mass transport in functionalized azo-polymers are far from deeply understood. To get some insight into those mechanisms on "microscopic" scale, we studied the directed photoinduced motion of single functionalized polymer chains under various types of polarized light illumination using Monte Carlo bond fluctuation model and our kinetic Monte Carlo model for photoinduced mass transport. We found sub-diffusive, diffusive and super-diffusive regimes of the dynamics of single chains at constant illumination and mostly super-diffusive regime for directed motion in the presence of the gradient of light intensity. This regime is more enhanced for long than for short chains and it approaches the ballistic limit for very long chains. We propose a physical picture of light-driven inscription of Surface Relief Gratings (SRG) as corresponding to a dynamical coexistence of normal and anomalous diffusion in various parts of the system. A simple continuous time random walk model of SRG inscription based on this physical picture reproduced the light-driven mass transport found in experiments as well as the fine structure of SRG.

2.
Nutrients ; 10(10)2018 Oct 21.
Article in English | MEDLINE | ID: mdl-30347877

ABSTRACT

Cardiovascular diseases are described as the leading cause of morbidity and mortality in modern societies. Therefore, the importance of cardiovascular diseases prevention is widely reflected in the increasing number of reports on the topic among the key scientific research efforts of the recent period. The importance of essential fatty acids (EFAs) has been recognized in the fields of cardiac science and cardiac medicine, with the significant effects of various fatty acids having been confirmed by experimental studies. Polyunsaturated fatty acids are considered to be important versatile mediators for improving and maintaining human health over the entire lifespan, however, only the cardiac effect has been extensively documented. Recently, it has been shown that omega-3 fatty acids may play a beneficial role in several human pathologies, such as obesity and diabetes mellitus type 2, and are also associated with a reduced incidence of stroke and atherosclerosis, and decreased incidence of cardiovascular diseases. A reasonable diet and wise supplementation of omega-3 EFAs are essential in the prevention and treatment of cardiovascular diseases prevention and treatment.


Subject(s)
Cardiovascular Diseases/prevention & control , Fatty Acids, Unsaturated , Dietary Supplements , Humans
3.
Curr Med Chem ; 23(8): 816-31, 2016.
Article in English | MEDLINE | ID: mdl-26795198

ABSTRACT

Polyunsaturated fatty acids (PUFAs) are crucial for our health and wellbeing; therefore, they have been widely investigated for their roles in maintaining human health and in disease treatment. Most Western diets include significant amount of saturated and omega-6 fatty acids and insufficient quantity of omega-3; however, the balance between omega-6 and omega-3 PUFA, in particular, is essential for the formation of pro- and anti-inflammatory lipids to promote health and prevent disease. As our daily diet affects our health, this paper draws attention to unique representatives of the omega-3 fatty acid group: alpha-linolenic acid and its derivatives. Recently, this has been shown to be effective in treating and preventing various diseases. It has been confirmed that omega-3 PUFAs may act as therapeutic agents as well and their significant role against inflammatory diseases, such as cardiovascular and neurodegenerative diseases, has been described. Some of nutritional factors have been described as a significant modifiers, which can influence brain elasticity and thus, effect on central nervous system functioning. Therefore, appropriate dietary management appears to be a non-invasive and effective approach to counteract neurological and cognitive disorders.


Subject(s)
Central Nervous System Diseases/diet therapy , Central Nervous System Diseases/prevention & control , Central Nervous System/metabolism , Fatty Acids, Omega-3/metabolism , Fatty Acids, Omega-3/therapeutic use , Central Nervous System Diseases/metabolism , Cognition Disorders/diet therapy , Cognition Disorders/metabolism , Cognition Disorders/prevention & control , Fatty Acids, Omega-3/chemistry , Humans , Molecular Structure
4.
Kardiol Pol ; 64(1): 68-71, 2006 Jan.
Article in Polish | MEDLINE | ID: mdl-16444636

ABSTRACT

A case of a 48 year old male scheduled for early invasive treatment of acute coronary syndrome with ST segment elevation is presented. Clinical suspicion of acute pulmonary embolism was undertaken because of normal coronary angiogram and was confirmed by pulmonary angiography. Differential diagnosis based on medical history, electrocardiogram and laboratory findings was discussed.


Subject(s)
Atrioventricular Node/physiopathology , Coronary Angiography/methods , Coronary Disease/diagnosis , Coronary Disease/physiopathology , Pulmonary Embolism/diagnosis , Acute Disease , Diagnosis, Differential , Early Diagnosis , Electrocardiography , Humans , Male , Middle Aged
5.
Kardiol Pol ; 59(11): 425-7, 2003 Nov.
Article in Polish | MEDLINE | ID: mdl-14668895

ABSTRACT

A case of 53-year-old male who was admitted to the hospital due to a chest pain, is presented. ECG showed ST elevation in precordial leads. The patient was successfully treated with primary angioplasty. On the third day of hospitalization, he collapsed with hypotension. Routine echocardiographic examination revealed signs of pulmonary embolism. An adequate pharmacotherapy was implemented and the patient improved. After 10 days of treatment and rehabilitation he was discharged home. The present case report points out on pulmonary embolism as a rare but potentially life-threatening complication of coronary angioplasty.


Subject(s)
Angioplasty, Balloon, Coronary/adverse effects , Myocardial Infarction/complications , Myocardial Infarction/therapy , Pulmonary Embolism/diagnosis , Pulmonary Embolism/etiology , Echocardiography , Electrocardiography , Humans , Male , Middle Aged , Pulmonary Embolism/therapy
6.
Kardiol Pol ; 58(2): 124-8, 2003 Feb.
Article in Polish | MEDLINE | ID: mdl-14504638

ABSTRACT

Four males aged 17-42 years with ST-T segment changes suggesting perimyocarditis or non-Q acute myocardial infarction are presented. Coronary angiography was performed to establish the final diagnosis. Three patients had normal coronary arteries; two of them had typical clinical signs of perimyocarditis whereas the third patient had less typical changes. The fourth patient was a smoker, had a family history of coronary heart disease and left ventricular dysfunction due to a non-Q wave apical infarction. In this patient coronary angiography revealed small atheromatous plaques in the distal part of left anterior descending artery as well as left main and right coronary artery spasm. Angiospastic aetiology of infarction and probable endothelial dysfunction due to myocarditis were diagnosed. The authors conclude that coronary angiography is not always helpful if clinical, electrocardiographic and biochemical signs of perimyocarditis are observed.


Subject(s)
Coronary Angiography , Electrocardiography , Myocardial Infarction/diagnosis , Myocarditis/diagnosis , Adult , Coronary Angiography/methods , Coronary Vessels/pathology , Diagnosis, Differential , Electrocardiography/methods , Humans , Male , Myocardial Infarction/diagnostic imaging , Myocarditis/diagnostic imaging
7.
Kardiol Pol ; 58(1): 42-4, 2003 Jan.
Article in Polish | MEDLINE | ID: mdl-14502302

ABSTRACT

We present a case of a 71-year-old male with exercise angina and two-vessel coronary artery disease (CAD). As the first step of treatment, the patient underwent successful coronary angioplasty with a stent implantation in the circumflex artery and remained free from angina for the following month. After this period, the patient underwent elective angioplasty of left anterior descending (LAD) coronary artery which was complicated by dissection, requiring implantation of two stents. Because of recurrent angina the patient underwent three months later another coronary angiography which revealed in-stent restenosis in LAD. The patient underwent repeated angioplasty with a good angiographic results, however, without cessation of angina Clinical and angiographic indications for percutaneous coronary interventions, according to the recent ACC/AHA guidelines, are discussed.


Subject(s)
Angina Pectoris/therapy , Angioplasty, Balloon, Coronary , Blood Vessel Prosthesis Implantation/adverse effects , Coronary Artery Disease/therapy , Coronary Restenosis/surgery , Stents , Aged , Angina Pectoris/diagnostic imaging , Coronary Artery Disease/diagnostic imaging , Coronary Restenosis/diagnostic imaging , Coronary Restenosis/etiology , Disease Progression , Graft Occlusion, Vascular/etiology , Graft Occlusion, Vascular/surgery , Humans , Male , Radiography , Recurrence , Retreatment , Stents/adverse effects , Time Factors , Treatment Outcome
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