ABSTRACT
Objective: This study explored the impact of a family intervention on the relapse rate of Chinese patients with alcohol dependence. Methods: A total of 151 male patients with alcohol dependence who were discharged from the Substance Dependence Department of the Wenzhou Seventh People's Hospital from January to December 2020 were selected. They were divided into the control (n = 73) and experimental (n = 78) groups. Patients in both groups received routine alcohol cessation treatment. Moreover, patients in the experimental group were followed up by a professional psychiatrist to carry out individual family intervention. The Family Function Rating Scale (FAD), a Self-made general information questionnaire, and the Chinese version of the Family Intimacy and Adaptability Scale (FACESI-CV) were performed. Re-drinking rate and readmission rate were assessed. Results: Family intervention could reduce relapse rate (31, 39.74%) and rehospitalization (27, 34.62%) compared with the control group. After family training, FAD factor scores were improved in the experiment group in comparison with the control group. Family training improved communication (18.2 ± 3.7), role (20.8 ± 2.5), emotional response (10.8 ± 1.8), emotional involvement (13.7 ± 1.2), behavioral control (19.8 ± 1.2), and overall functionality (23.5 ± 2.1) in the experiment group in comparison with the control group. After family training, intimacy (70.5 ± 8.7) and adaptability (64.1 ± 6.9) in the experiment group was higher than in the control group. After family intervention, Michigan Alcohol Dependence Scale (MAST) (9.21 ± 0.68) and Short-Form 36 (SF-36) (80.32 ± 4.47) in the experiment group were higher than the control group. Conclusion: Family intervention for families of patients with alcohol dependence can improve their family function, increase their family intimacy and adaptability, and reduce the rate of relapse.
Subject(s)
Alcoholism , Recurrence , Humans , Male , Alcoholism/psychology , Adult , China , Middle Aged , Surveys and Questionnaires , Family Therapy/methods , Family/psychologyABSTRACT
In the title compound, C(15)H(13)N(3)O(4), the pyridine and benzene rings are nearly perpendicular [dihedral angle = 84.24â (5)°]. In the crystal structure, classical O-Hâ¯N hydrogen bonding between the OH group of the carboxyl unit and a neighbouring pyridine ring N atom and N-Hâ¯O hydrogen bonding between the imine NH group and a neighbouring O atom of an acyl unit, together with complementary non-classical C-Hâ¯O hydrogen bonds between carboxyl O atoms and neighbouring CH groups, link the mol-ecules into a three-dimensional system.
ABSTRACT
In the title compound, [Cu(C(13)H(13)Cl(2)NO(3))(C(3)H(7)NO)], the Cu(II) atom is coordinated in a slightly distorted square-planar geometry by two O atoms and one N atom from the tridentate chiral ligand 2-[(3,5-dichloro-2-oxidobenzyl-idene)amino]-3-methyl-penta-noate and by one O atom from dimethyl-formamide. In the crystal structure, the Cu atom forms contacts with Cl and O atoms of two units (Cuâ¯Cl and Cuâ¯O = 3.401 and 2.947â Å, respectively), thereby forming an approximately octa-hedral arrangement. A three-dimensional network is constructed through Clâ¯Cu, Oâ¯Cu, Clâ¯Cl contacts and C-Hâ¯O hydrogen bonds.
