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1.
Phys Rev Lett ; 128(21): 216403, 2022 May 27.
Article in English | MEDLINE | ID: mdl-35687437

ABSTRACT

Inspired by the newly emergent valleytronics, great interest has been attracted to the topological valley transport in classical metacrystals. The presence of nontrivial domain-wall states is interpreted with a concept of valley Chern number, which is well defined only in the limit of small band gap. Here, we propose a new visual angle to track the intricate valley topology in classical systems. Benefiting from the controllability of our acoustic metacrystals, we construct Weyl points in synthetic three-dimensional momentum space through introducing an extra structural parameter (rotation angle here). As such, the two-dimensional valley-projected band topology can be tracked with the strictly quantized topological charge in three-dimensional Weyl crystal, which features open surface arcs connecting the synthetic Weyl points and gapless chiral surface states along specific Weyl paths. All theoretical predictions are conclusively identified by our acoustic experiments. Our findings may promote the development of topological valley physics, which is less well defined yet under hot debate in multiple physical disciplines.

2.
J Biomed Mater Res B Appl Biomater ; 109(1): 50-59, 2021 01.
Article in English | MEDLINE | ID: mdl-32627333

ABSTRACT

Rapid and convenient wound healing is crucial for reducing potential post-traumatic wound complications. In this study, a temperature-sensitive polymer of poly-(HEMA-co-NIPAM) (PHN) was synthesized by free-radical polymerization, in which the solution quickly underwent a sol-gel transition above 29°C, thus responding to a typical body temperature and facilitating wound sealing. PHN solution incorporated with copper ions (PHN-Cu) not only exhibited excellent antibacterial properties, but also expedited wound closure and facilitated tissue angiogenesis. The in vivo and in vitro experiments showed that the PHN-Cu had a higher wound closure rate and demonstrated an ability to promote skin tissue angiogenesis. Such a versatile, convenient aqueous solution could enable nonprofessionals to promptly treat wounds in a short time after injury, thus providing suitable conditions for later treatment, and can be used as a convenient method to clean wounds.


Subject(s)
Anti-Bacterial Agents/chemistry , Copper/chemistry , Polyamines/chemistry , Polyhydroxyethyl Methacrylate/analogs & derivatives , Wound Healing/drug effects , Animals , Anti-Bacterial Agents/pharmacology , Cell Movement/drug effects , Cell Proliferation/drug effects , Copper/pharmacology , Drug Compounding , Escherichia coli/drug effects , Humans , Male , Phase Transition , Polyhydroxyethyl Methacrylate/chemistry , Rats, Sprague-Dawley , Staphylococcus aureus/drug effects , Transition Temperature , Treatment Outcome
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