ABSTRACT
Background: The rising incidence of emergency stroke cases emphasizes the need for refining care strategies. This study addresses this critical need to assess the effectiveness of optimized emergency care pathways for improving patient outcomes. Objective: This study evaluates the efficacy of optimized emergency care pathways for stroke patients in emergency situations. Methods: A total of 60 emergency stroke cases admitted to our hospital between June 2020 and June 2022 were included. Patients were assigned to a control group and an observation group based on care modalities in a 1:1 ratio. The control group received conventional emergency care, while the observation group underwent the optimized emergency care pathway. Baseline data, resuscitation effects, clinical outcomes, serum inflammatory factor levels, prognosis, nursing satisfaction, and related indices were recorded and compared between the two groups. Results: Patients in the observation group exhibited significantly reduced resuscitation and treatment times compared to the control group (P < .001). The observation group had fewer deaths within 48 hours (P < .001). Serum levels of interleukin (IL)-6, IL-8, and Intercellular Adhesion Molecule-1 (ICAM-1) decreased significantly in the observation group compared to the control group (P < .001). The observation group also had fewer cases of disability, vegetation, and death (6.66% vs. 40%, P < .001). Patient satisfaction in the observation group was 90%, significantly higher than the control group (20%, P < .001). Conclusions: The optimized emergency care pathway proves effective for emergency stroke patients, enhancing resuscitation, clinical outcomes, and prognosis while reducing inflammatory factors. Furthermore, it elevates patient satisfaction, warranting widespread implementation.
ABSTRACT
2D Ruddlesden-Popper (RP) perovskites have appeared as a promising prospective material owing to their tunable optoelectronic peculiarities and structural stability. The choice of interlayer cations greatly influences the performance of the 2D RP perovskites. In this study, through theoretical calculations and experimental investigation, we demonstrate the intrinsic and device performance differences between two perovskites based on cations of thiophenemethylamine (TMA) and thiopheneethylamine (TEA). Using density functional theory (DFT) calculations, it exposes that as compared to (TMA)2PbI4, (TEA)2PbI4 exhibits more pronounced distortion of [PbI6]4- units and possesses a wider band gap and larger effective mass. The experimental results on the TMA- and TEA-based 2D perovskites further show that when TEA is used as the interlayer cation, the crystallization process tends to form more low-n phases, which hinder charge transfer and decrease light harvesting. On the other hand, when TMA is used as the interlayer cation, excessive low-n phases are not observed, and the thin film exhibits excellent quality with significantly improved electron mobility. The (TMA)2(FA)n-1PbnI3n+1 (n = 5) perovskite device shows a remarkable conversion efficiency of 16.56%, much higher than that of TEA-based devices (PCE = 2.58%). Moreover, the unencapsulated devices based on TMA were able to maintain 88% of their initial efficiency even after being exposed to the environment (RT, RH = 30 ± 5%) for a duration of 1080 h. These findings provide important insights into the differences between thiophene-based cations and the selection of organic interlayer cations for 2D RP perovskite solar cells.
ABSTRACT
Objective: To investigate the clinical effects of applying a prospective nursing model combined with humanistic care in patients with acute stroke. Methods: A total of 160 patients with acute stroke who received treatment at The First Affiliated Hospital of Soochow University from July 2019 to July 2021 were selected as the study subjects. According to different nursing methods, the patients were divided into a control group of 80 patients, who received basic routine nursing care, and an observation group of 80 patients, who received a prospective nursing model combined with humanistic care. Hemodynamic status, the concentrations of interleukin-6 (IL-6), IL-8, and tumor necrosis factor, concentrations, SF-36 Survey scores, Self-Rating Anxiety Scale and Self-Rating Depression Scale scores, and nursing satisfaction were compared between the 2 groups. Results: The hemodynamic status of the patients in the observation group, as measured by heart rate, arterial pressure, and blood oxygen saturation, was significantly improved compared with patients in the control group (P < .05). The concentrations of interleukin-6 (IL-6), IL-8, and tumor necrosis factor were significantly lower in the observation group than in the control group (P < .05). The SF-36 Survey scores were higher in the observation group than in the control group (P < .05). The Self-Rating Anxiety Scale and Self-Rating Depression Scale scores were lower in the observation group than in the control group (P < .05). Nursing satisfaction was higher in the observation group than in the control group (P <.05). Conclusion: The application of a prospective nursing model combined with humanistic care in patients with acute stroke can effectively reduce concentrations of inflammatory factors, improve blood oxygen saturation, alleviate negative emotions such as depression and anxiety, and enhance the patients' quality of life and nursing satisfaction. Therefore, this model is worthy of clinical promotion and application.
