Common Problems of Traditional Chinese Medicine Effervescent Tablets and Prospect Analysis of Powder Modification Technology / 中国实验方剂学杂志

Traditional Chinese medicine （TCM） effervescent tablets have the characteristics of rapid disintegration， good taste， and convenient taking， but there are some technical difficulties in the preparation and storage process， which are mainly reflected in the sticking， easy moisture absorption， poor compressibility， and poor stability. The basic physical properties of TCM powder （extract powder， raw powder） are the main cause of these technical problems， and also the key to control the quality of TCM effervescent tablets. Powder modification technology has shown good effects in solving the above problems. The author intended to review the research in the above aspects in recent years， and proposed the following strategies for applying powder modification technology to solve the problems in the production process of TCM effervescent tablets from the three aspects of raw materials， excipients and preparation intermediates：①The application of co-processing technology to the treatment of raw materials and auxiliary materials can solve the problems of sticking， poor compressibility， delayed disintegration， and poor stability. ②Using surface coating technology to treat raw materials and preparation intermediates can improve poor fluidity， poor compressibility and delayed disintegration. ③The hygroscopicity of the preparation can be reduced by using microencapsulation technology to treat the raw material. ④The inclusion technology can improve the clarity and stability of the preparation.

Enhanced Electrochemical Performance of Fe0.74Sn5@Reduced Graphene Oxide Nanocomposite Anodes for Both Li-Ion and Na-Ion Batteries.

The recently found intermetallic FeSn5 phase with defect structure Fe0.74Sn5 has shown promise as a high capacity anode for lithium-ion batteries (LIBs). The theoretical capacity is as high as 929 mAh g(-1) thanks to the high Sn/Fe ratio. However, despite being an alloy, the cycle life remains a great challenge. Here, by combining Fe0.74Sn5 nanospheres with reduced graphene oxide (RGO) nanosheets, the Fe0.74Sn5@RGO nanocomposite can achieve capacity retention 3 times that of the nanospheres alone, after 100 charge/discharge cycles. Moreover, the nanocomposite also displays its versatility as a high-capacity anode in sodium-ion batteries (SIBs). The enhanced cell performance in both battery systems indicates that the Fe0.74Sn5@RGO nanocomposite can be a potential anode candidate for the application of Li-ion and Na-ion battery.