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Zhongguo Zhong Yao Za Zhi ; 37(19): 2898-901, 2012 Oct.
Article in Chinese | MEDLINE | ID: mdl-23270229

ABSTRACT

Chemical constituents in ethyl acetate and butanol fractions of ethanol extracts from Acorus tatarinowii were separated by column chromatography. Bufo skeletal muscle fatigue model was established to study the anti-fatigue activity of separated compounds. Five compounds were separated and identified by spectroscopic analysis as acoramone(1),cycloartenone(2),2,4,5-trimethoxyl-2'-butoxy-1,2-phenyl propandiol(3),5-hydroxymethyl furfural(4), and 5-butoxymethyl furfural(5). Compound 3 was a new compound, and compounds 2 and 5 were separated from this plant for the first time. Compound 4 exhibited a notable anti-fatigue activity.


Subject(s)
Acorus/chemistry , Plant Extracts/chemistry , Plant Extracts/pharmacology , Animals , Bufonidae , Fatigue/drug therapy , Muscle, Skeletal/drug effects
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