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J Asian Nat Prod Res ; 17(4): 352-6, 2015.
Article in English | MEDLINE | ID: mdl-25465438

ABSTRACT

Two new compounds 5-[4'-(4″-hydroxybenzyl)-3'-hydroxybenzyloxymethyl]-furan-2-carbaldehyde (1) and 5-[4'-(4″-hydroxybenzyl)-3'-hydroxybenzyl]-furan-2-carbal-dehyde (2), together with two known 5-(4-hydroxbenzyloxymethyl)-furan-2-carbaldehyde] (3) and 5-(hydroxymethyl)-2-furaldehyde (4), were isolated from the rhizome of Gastrodia elata. Their structures were elucidated by spectroscopic analysis and comparison of their spectral data with those reported previously. All compounds exhibited weak or no cytotoxicity against human colon carcinoma cell line (HT-29) and human chronic myelogenous leukemia cell line (K-562).


Subject(s)
Drugs, Chinese Herbal/isolation & purification , Furaldehyde/analogs & derivatives , Gastrodia/chemistry , Drug Screening Assays, Antitumor , Drugs, Chinese Herbal/chemistry , Drugs, Chinese Herbal/pharmacology , Furaldehyde/chemistry , Furaldehyde/isolation & purification , Furaldehyde/pharmacology , HT29 Cells , Humans , Molecular Structure , Phenols/chemistry , Rhizome/chemistry
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