ABSTRACT
The introduction of functional groups into metal organic frameworks has great potential for enhancement in adsorption performance of nitrosamines using solid phase microextraction (SPME). However, pre-functionalization and post-modification generally suffer from the same limitation that the additional functional groups occupy the free volume and thereby decreasing pore volume and special surface area. Herein, we use a modulator-induced defect-formation strategy to prepare the 8-aminocaprylic acid doped UIO-66 (Am-UIO-66) with high adsorption capacity of nitrosamines. Then, the as-synthesized UIO-66 and Am-UIO-66 were fabricated as SPME fibers exhibiting good adsorption capacity towards nitrosoamines. The reason was that the 8-aminocaprylic acid creates structural defects and additional pore spaces of Am-UIO-66, thus increases the specific surface area as well as pore volume. Finally, the Am-UIO-66-coated SPME fiber was successfully applied to the determination of nitrosamines migration from latex gloves and achieved good linearity (20-2000ngL-1), satisfactory recoveries (85.2-112.8%) and rather low LODs (2.61-6.12ngL-1), by coupling with gas chromatography-mass spectrometry (GC-MS).
