ABSTRACT
An approach for the cryptographic security enhancement of encryption is proposed and analyzed. The enhancement is based on the employment of a coding scheme and degradation of the ciphertext. From the perspective of the legitimate parties that share a secret key, the degradation appears as a transmission of the ciphertext through a binary erasure channel. On the other hand, from the perspective of an attacker the degradation appears as a transmission of the ciphertext over a binary deletion channel. Cryptographic security enhancement is analyzed based on the capacity of the related binary deletion channel. An illustrative implemementation framework is pointed out.
ABSTRACT
Mucolipidosis III gamma is an autosomal recessive disorder with defective phosphorylation and trafficking of lysosomal enzymes. In a Chinese family with three siblings, linkage analysis revealed positive linkage of the family to GNPTG. Direct DNA sequence analysis identified two novel compound heterozygous mutations, c.471delC in exon 7 and IVS4-1G>C, in three patients. The two mutations cause frameshift and abnormal splicing, respectively, and represent the first series of GNPTG mutations in the Chinese population.