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1.
Arch Gynecol Obstet ; 293(5): 1049-52, 2016 May.
Article in English | MEDLINE | ID: mdl-26525696

ABSTRACT

PURPOSE: To evaluate the ovarian reserve after laparoscopic cystectomy with suturing in patients with endometriomas. METHODS: A total of 80 women with unilateral or bilateral endometriomas underwent laparoscopic cystectomy using sutures for hemostasis after the excision of ovarian cysts. Serum levels of antimullerian hormone (AMH) and FSH were measured at the day 3 of menstrual cycles preoperatively, 6 and 12 months postoperatively. RESULTS: In the bilateral endometrioma group, serum AMH level decreased significantly from the baseline (4.68 ± 2.87 ng/ml) to 6 months (3.05 ± 1.99 ng/ml) and 12 months (2.26 ± 1.88 ng/ml) postoperatively, whereas the FSH level increased significantly from baseline to 12 months postoperatively (P < 0.05). Those patients with unilateral endometriomas also had lower levels of AMH in 6 and 12 months after operation. When compared between unilateral and bilateral endometrioma group, the rate of AMH decline 6 and 12 months and the rate of FSH increase 12 months postoperatively reached statistical significance (P < 0.05). CONCLUSIONS: The changes of the AMH and FSH values suggest that the ovarian reserve is obviously reduced in spite of suturing technology used as a method of hemostasis after stripping ovarian endometriomas, especially in those with bilateral cysts. The protective effect of the ovarian suturing for ovarian reserve may be marginal.


Subject(s)
Anti-Mullerian Hormone/blood , Cystectomy , Endometriosis/surgery , Laparoscopy/methods , Ovarian Reserve , Sutures/adverse effects , Adult , Female , Follicle Stimulating Hormone/blood , Humans , Middle Aged , Ovarian Cysts/surgery , Postoperative Period , Prospective Studies , Treatment Outcome
2.
Gynecol Obstet Invest ; 76(3): 151-7, 2013.
Article in English | MEDLINE | ID: mdl-23949246

ABSTRACT

AIM: To describe our experience with various interventions for caesarean scar pregnancies (CSPs) based on the myometrial thickness between the gestational mass and the bladder. METHODS: All patients were initially administered methotrexate. Then, the appropriate therapies hysteroscopy alone or combined with uterine artery embolization (group A) and direct laparoscopy alone or combined with laparoscopic uterine artery occlusion (group B) was selected based on the myometrial thickness between the gestational mass and the bladder. RESULTS: The uteri of all 53 patients with CSPs were conserved; no conversion to laparotomy or blood transfusion was required. Uterine rupture occurred in one case during surgery in group A. The operative time in group B was longer than group A (42 ± 18 vs. 80 ± 33 min; p = 0.022). The two groups were also similar with respect to other characteristics (p > 0.05). CONCLUSION: Myometrial thickness should be considered during the management of CSPs. Surgical approaches in the treatment of CSPs using 2-mm boundaries may yield an optimal clinical outcome.


Subject(s)
Cicatrix/pathology , Hysteroscopy/methods , Methotrexate/therapeutic use , Myometrium/anatomy & histology , Pregnancy, Ectopic/pathology , Pregnancy, Ectopic/therapy , Urinary Bladder/anatomy & histology , Adult , Chi-Square Distribution , Chorionic Gonadotropin, beta Subunit, Human/blood , Cicatrix/therapy , Female , Humans , Operative Time , Pregnancy , Pregnancy, Ectopic/blood , Uterine Artery Embolization/methods
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