Unusual N-H activation of 2-aminopyrimidine: supramolecular assembly into an Ag(I) metal-organic framework.

A rare example of coordination at the amino group of NH2 pym (2-aminopyrimidine) relevant to N-H activation is described that leads to a novel Ag(I) -imide 3D metal-organic framework (MOF). The coordination of Ag(I) to NH2 pym produced an electron-withdrawing effect and thus increased its acidity, which facilitated the N-H activation and the subsequent formation of the Ag-imide bond. A cooperative metalation/deprotonation process for the N-H activation of NH2 pym is suggested. Interestingly, photoluminescence of 1 is switched on at the low temperature of 77 K.

Sidearm effects in the enantioselective cyclopropanation of alkenes with aryldiazoacetates catalyzed by trisoxazoline/Cu(I).

A highly enantioselective cyclopropanation of alkenes with phenyldiazoacetates catalyzed by CuPF6(CH3CN)4/trisoxazoline has been developed.