ABSTRACT
Objective To analysis and research the clinical pathological characteristics with papillary thyroid carcinoma(PTC)and nodular goiter.Methods 100 cases with thyroid disease were selected,the preoperative ultra-sound diagnosis and pathological diagnosis results were compared,and pathological features were analyzed.Results Ultrasound results:ther were 72 cases with PTC,and 28 cases with NG,and pathologically confirmed 48 cases with PTC,52 cases with NG.The difference of two diagnostic result was statistically significant (χ2 =5.263,P <0.05). Compared with 48 PTC cases,the ratio of single nodule in 52 NG patients was smaller,while multiple nodules and cystic lesions proportion were higher,the differences were statistically significant (χ2 =58.19,73.97,25.40,all P <0.05).PTC was characterized by solid nodules of gray matter,often located near the thyroid capsule.Large tumors may be cystic.NG was characterized by single or multiple nodules,with different size,and some nodules with incomplete capsule,some with thick fibrous capsule.Nodular cystic necrosis hemorrhage was common.Conclusion Ultrasound diagnosis and can make a more accurate judgment between NG and PTC,but there are still misdiagnosed on the two diseases,for PTC and NG accurate judgment also need to rely on pathological identification,so grasping the pathologi-cal features of both can improve diagnostic accuracy.
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Objective To study the clinicopathologic characteristics of pulmonary sclerosing hemangioma(SH).Method Eleven cases of SH were studied by the clinical data and immunohistochemistry and review of the literature.Results SH has a characteristic architecture composed of round cell and surface cubic cell.It has a variety of tissular structure,mainly expression with four regions that contain solid regions,papillary regions,angiomatoid regions and sclerosing regions.Immunohistochemically,these two kinds of cells were both positive for TTF-1 and EMA.Conclusions SH is a tumor that originates from the epithelial cell of primary respiratory tract.Both the solid round cells and surface cubic cells are neoplastic.SH should differentiate with inflammatory,typeⅡpneumocyte papillary tumor,alveolus adenoma and typical carcinoid tumors.The parts of SH have invade grow tendency.Surgical cure of SH is suited for operating a lobe of the lung but not just peel of the tumor.
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Objective To investigate the clinical and pathological characters and seize the diagnostic main points of minimal deviation adenocarcinoma of cervix to improve the accuracy of pathological diagnosis. Methods A clinic pathological review of 6 cases with minimal deviation adenocarcinoma was analyzed retrospectively. Results The main clinical symptoms were watery leucorrhagia, enlargement of the cervix with erosin and hardening. The pathological findings included hyperplasic and mild abnormality of the glands, invasion effects into the stroma could be observed in some glands and abortive glands with desmoplastic changes, or edema and inflammatory infiltration around the glands were also observed. Conclusion The detection rate of minimal deviation adenocarcinoma may increase by triple combination of clinic, cytology and histology.
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Objective Investigate the clinicopathological characteristics of h?rthle cell tumors of the thyroid. Methods Sixteen cases of HCT were studied by the clinicopathological study and immunohistochemical and review of the literature. Results There were 13 cases of h?rthle cell adenomas, 5 h?rthle cell follicular carcinomas. Immunostains showed that almost all benign and malignant HCT expressed TG, vimentin, S-100 protein. Conclusions HCT is a potential malignant tumor with a defined pathologic feature. It should be follow up for a longer time to their biological behaviors. To distinguish between the benign and the malignant depends on traditional encapsulation, and whether there is a blood vessel invasion or metastasis.
