Prevalence of sexually risky behaviors among Mexican medical students.

University students are at high risk of sexually transmitted infections due to the lack of adequate sexual education, as well as multiple associated factors, which lead to risky sexual practices. It is important to update data about sexual behaviors to identify the main factors associated with sexually risky behaviors. The present study aimed to evaluate the current prevalence of sexually risky practices in medical students. A cross-sectional study was conducted among medical students through an anonymous self-administered online questionnaire including demographic characteristics and sexual behaviors. We used descriptive statistics and multivariable regression to analyze the data collected. A total of 1520 undergraduate medical students aged between 18 and 28 years old were included in the study. Sixty percent of the students were sexually active with a higher proportion in men (70%), likewise, they had an earlier sexual debut (16.5 vs 16.9 years old), and a greater number of lifetime sexual partners than women (3.8 vs 2.2). The main sexual activity in both groups was vaginal sex with high use of condoms (75%), however, most of them (67%) reported having unprotected oral sex. Logistic regression analysis showed that condomless sex was associated with having oral sex, anal sex, and being female. The findings of this study showed that medical university students are involved in risky sexual behaviors, the major risk factor was unprotected oral sex. Based on these results, we recommended designing interventions to improve sexual education and preventive approaches from early stages such as in middle school students to mitigate sexually transmitted infections among medical university students.

The Role of Propolis as a Natural Product with Potential Gastric Cancer Treatment Properties: A Systematic Review.

Gastric cancer is one of the most common, aggressive, and invasive types of malignant neoplasia. It ranks fifth for incidence and fourth for prevalence worldwide. Products of natural origin, such as propolis, have been assessed for use as new complementary therapies to combat cancer. Propolis is a bee product with antiproliferative and anticancer properties. The concentrations and types of secondary metabolites contained in propolis mainly vary according to the geographical region, the season of the year, and the species of bees that make it. The present study is a systematic review of the main articles related to the effects of propolis against gastric cancer published between 2011 and 2021 in the PubMed and Science Direct databases. Of 1305 articles published, only eight studies were selected; among their principal characteristics was the use of in vitro analysis with cell lines from gastric adenocarcinoma and in vivo murine models of the application of propolis treatments. These studies suggest that propolis arrests the cell cycle and inhibits proliferation, prevents the release of oxidizing agents, and promotes apoptosis. In vivo assays showed that propolis decreased the number of tumors by regulating the cell cycle and the expression of proteins related to apoptosis.

Antifungal Activity of Mexican Propolis on Clinical Isolates of Candida Species.

Infections caused by micro-organisms of the genus Candida are becoming a growing health problem worldwide. These fungi are opportunistic commensals that can produce infections-clinically known as candidiasis-in immunocompromised individuals. The indiscriminate use of different anti-fungal treatments has triggered the resistance of Candida species to currently used therapies. In this sense, propolis has been shown to have potent antimicrobial properties and thus can be used as an approach for the inhibition of Candida species. Therefore, this work aims to evaluate the anti-Candida effects of a propolis extract obtained from the north of Mexico on clinical isolates of Candida species. Candida species were specifically identified from oral lesions, and both the qualitative and quantitative anti-Candida effects of the Mexican propolis were evaluated, as well as its inhibitory effect on C. albicans isolate's germ tube growth and chemical composition. Three Candida species were identified, and our results indicated that the inhibition halos of the propolis ranged from 7.6 to 21.43 mm, while that of the MFC and FC50 ranged from 0.312 to 1.25 and 0.014 to 0.244 mg/mL, respectively. Moreover, the propolis was found to inhibit germ tube formation (IC50 ranging from 0.030 to 1.291 mg/mL). Chemical composition analysis indicated the presence of flavonoids, including pinocembrin, baicalein, pinobanksin chalcone, rhamnetin, and biochanin A, in the Mexican propolis extract. In summary, our work shows that Mexican propolis presents significant anti-Candida effects related to its chemical composition, and also inhibits germ tube growth. Other Candida species virulence factors should be investigated in future research in order to determine the mechanisms associated with antifungal effects against them.

Flavonoids Present in Propolis in the Battle against Photoaging and Psoriasis.

The skin is the main external organ. It protects against different types of potentially harmful agents, such as pathogens, or physical factors, such as radiation. Skin disorders are very diverse, and some of them lack adequate and accessible treatment. The photoaging of the skin is a problem of great relevance since it is related to the development of cancer, while psoriasis is a chronic inflammatory disease that causes scaly skin lesions and deterioration of the lifestyle of people affected. These diseases affect the patient's health and quality of life, so alternatives have been sought that improve the treatment for these diseases. This review focuses on describing the properties and benefits of flavonoids from propolis against these diseases. The information collected shows that the antioxidant and anti-inflammatory properties of flavonoids play a crucial role in the control and regulation of the cellular and biochemical alterations caused by these diseases; moreover, flavones, flavonols, flavanones, flavan-3-ols, and isoflavones contained in different worldwide propolis samples are the types of flavonoids usually evaluated in both diseases. Therefore, the research carried out in the area of dermatology with bioactive compounds of different origins is of great relevance to developing preventive and therapeutic approaches.

[Experiences of medical students belonging to sexual and gender diversity: a systematic review]. / Las experiencias de los estudiantes de medicina LGBTQ+ durante su formación: Una revisión sistemática.

BACKGROUND: Students belonging to sexual and gender diversity experience chronic stress due to stigmatization and discrimination. AIM: To identify the experiences of lesbian, gay, bisexual, transgender/transsexual, and queer (LGBTQ+) medical students. MATERIAL AND METHODS: Systematic literature review using the PRISMA protocol in PubMed, ERIC, EMBASE, and LILACS databases. Articles published in Spanish or English were considered. Three authors independently reviewed and synthesized information from the selected articles, according to the PRISMA criteria. RESULTS: Fifteen studies met the inclusion criteria. Forty-three experiences were reported, which were finally classified into four categories: i) Relationship between peers in the educational context (23%), ii) Relationship between students and teachers in the educational context (23%), iii) Relationship with the educational institution (34%), and iv) Curriculum and training experience (19%). The relationship with the educational institution was identified as the most relevant category. Students with a strong sense of belonging to their institution were more likely to be persistent and make an effort in learning. The second most relevant experiences, mainly negative, derive from interactions with peers and teachers. CONCLUSIONS: LGBTQ+ medical students still experience more discrimination than inclusion during their training. Therefore, medical schools should render medical education a more inclusive space for the LGBTQ+ population.

Temporal Dynamics of T Helper Populations in the Proximal Small Intestine after Oral Bovine Lactoferrin Administration in BALB/c Mice.

Bovine lactoferrin (bLf), a component of milk and a dietary supplement, modulates intestinal immunity at effector and inductor sites. Considering the regional difference in intestinal compartments and the dynamics of local cytokine-producing cells in the gut across time, the aim of this work was to characterize the effects of bLf on the proximal small intestine in a BALB/c murine model of oral administration. Male BALB/c mice were treated with oral bLf vs. saline control as mock by buccal deposition for 28 days. Intestinal secretions were obtained at different time points and cells were isolated from Peyer's patches (PP) and lamina propria (LP) of the proximal small intestine as representative inductor and effector sites, respectively. Total and specific anti-bLF IgA and IgM were determined by enzyme-immuno assay; the percentages of IgA+ and IgM+ plasma cells (PC) and cytokine-producing CD4+ T cells of PP and LP were analyzed by flow cytometry. We found that total and bLf-specific IgA and IgM levels were increased in the intestinal secretions of the bLf group in comparison to mock group and day 0. LP IgA+ PC and IgM+ PC presented an initial elevation on day 7 and day 21, respectively, followed by a decrease on day 28 in comparison to mock. Higher percentages of CD4+ T cells in LP were found in the bLf group. Cytokines-producing CD4+ T cells populations presented a pattern of increases and decreases in the bLf group in both LP and PP. Transforming growth factor beta (TGF-ß)+ CD4+ T cells showed higher percentages after bLf administration with a marked peak at day 21 in both LP and PP in comparison to mock-treated mice. Oral bLf exhibits complex immune properties in the proximal small intestine, where temporal monitoring of the inductor and effector compartments reveals patterns of rises and falls of different cell populations. Exceptionally, TGF-ß+ CD4+ T cells show consistent higher numbers after bLf intervention across time. Our work suggests that isolated measurements do not show the complete picture of the modulatory effects of oral bLf in immunological sites as dynamic as the proximal small intestine.

Autophagy inhibition in breast cancer cells induces ROS-mediated MIF expression and M1 macrophage polarization.

Autophagy can function as a survival mechanism for cancer cells and therefore, its inhibition is currently being explored as a therapy for different cancer types. For breast cancer, triple negative breast cancer (TNBC) is the subtype most sensitive to the inhibition of autophagy; but its inhibition has also been shown to promote ROS-dependent secretion of macrophage migration inhibitory factor (MIF), a pro-tumorigenic cytokine. In this work, we explore the role of MIF in breast cancer, the mechanism by which autophagy inhibition promotes MIF secretion and its effects on neighboring cancer cell signaling and macrophage polarization. We analyzed MIF mRNA expression levels in tumors from breast cancer patients from different subtypes and found that Luminal B, HER2 and Basal subtypes, which are associated to high proliferation, displayed high MIF levels. However, MIF expression had no prognostic relevance in any breast cancer subtype. In addition, we found that autophagy inhibition in 66cl4 TNBC cells increased intracellular Reactive Oxygen Species (ROS) levels, which increased MIF expression and secretion. MIF secreted from 66cl4 TNBC cells induced the activation of MIF-regulated pathways in syngeneic cell lines, increasing Akt phosphorylation in 4T1 cells and ERK phosphorylation in 67NR cells. Regarding MIF/ chemokine receptors, higher levels of CD74 and CXCR2 were found in TNBC tumor cell lines when compared to non-tumorigenic cells and CXCR7 was elevated in the highly metastatic 4T1 cell line. Finally, secreted MIF from autophagy deficient 66cl4 cells induced macrophage polarization towards the M1 subtype. Together, our results indicate an important role for the inhibition of autophagy in the regulation of ROS-mediated MIF gene expression and secretion, with paracrine effects on cancer cell signaling and pro-inflammatory repercussions in macrophage M1 polarization. This data should be considered when considering the inhibition of autophagy as a therapy for different types of cancer.

Las experiencias de los estudiantes de medicina LGBTQ+ durante su formación: Una revisión sistemática / Experiences of medical students belonging to sexual and gender diversity: a systematic review

Background: Students belonging to sexual and gender diversity experience chronic stress due to stigmatization and discrimination. Aim: To identify the experiences of lesbian, gay, bisexual, transgender/transsexual, and queer (LGBTQ+) medical students. Material and Methods: Systematic literature review using the PRISMA protocol in PubMed, ERIC, EMBASE, and LILACS databases. Articles published in Spanish or English were considered. Three authors independently reviewed and synthesized information from the selected articles, according to the PRISMA criteria. Results: Fifteen studies met the inclusion criteria. Forty-three experiences were reported, which were finally classified into four categories: i) Relationship between peers in the educational context (23%), ii) Relationship between students and teachers in the educational context (23%), iii) Relationship with the educational institution (34%), and iv) Curriculum and training experience (19%). The relationship with the educational institution was identified as the most relevant category. Students with a strong sense of belonging to their institution were more likely to be persistent and make an effort in learning. The second most relevant experiences, mainly negative, derive from interactions with peers and teachers. Conclusions: LGBTQ+ medical students still experience more discrimination than inclusion during their training. Therefore, medical schools should render medical education a more inclusive space for the LGBTQ+ population.

Effects of Propolis on Infectious Diseases of Medical Relevance.

Infectious diseases are a significant problem affecting the public health and economic stability of societies all over the world. Treatment is available for most of these diseases; however, many pathogens have developed resistance to drugs, necessitating the development of new therapies with chemical agents, which can have serious side effects and high toxicity. In addition, the severity and aggressiveness of emerging and re-emerging diseases, such as pandemics caused by viral agents, have led to the priority of investigating new therapies to complement the treatment of different infectious diseases. Alternative and complementary medicine is widely used throughout the world due to its low cost and easy access and has been shown to provide a wide repertoire of options for the treatment of various conditions. In this work, we address the relevance of the effects of propolis on the causal pathogens of the main infectious diseases with medical relevance; the existing compiled information shows that propolis has effects on Gram-positive and Gram-negative bacteria, fungi, protozoan parasites and helminths, and viruses; however, challenges remain, such as the assessment of their effects in clinical studies for adequate and safe use.

Los atributos de un tutor clínico de excelencia: una revisión sistemática

Knowing what characterizes an excellent teacher is relevant to guide training, evaluation, and continuous improvement of the clinical teacher. We performed a systematic review using the PRISMA protocol, aiming to identify the attributes of an excellent clinical teacher. MEDLINE, ERIC, ScienceDirect, and Scopus databases were searched for articles published in English and Spanish, between 2007 and 2019. Two independent reviewers extracted and synthesized data from articles that met the PRISMA pre-established criteria. Twelve studies met the inclusion criteria. Of the 106 attributes reported by the studies, 49 (46,2%) were generic. The most frequently mentioned attribute was respectfulness. Forty-six attributes (43,3%) were pedagogical. Feedback and planning were those most frequently mentioned. Eleven attributes (10,3%) were disciplinary and clinical skills was the most mentioned. We conclude that generic and pedagogical dimensions had a greater representation in the literature, in comparison with the disciplinary dimension. This could be explained, considering that having adequate clinical skills is the minimal necessary requisite to become a clinical teacher, but does not make a difference in how their performance is perceived, contrary to the generic and pedagogical dimensions.

Ameloplastia positiva en relación céntrica como método auxiliar durante la finalización en el tratamiento de ortodoncia en un paciente bruxista / Positive ameloplasty in centric relationship as an auxiliary method during finalization in the orthodontic treatment in a bruxist patient

A continuación se presenta un caso de un paciente de 12 años de edad, con antecedente de bruxismo, con biotipo mesofacial, tercio inferior dolicofacial, hipertonicidad muscular en maseteros, cierre labial forzado con incompetencia labial de 4 milímetros con dolor en sinoviales anteriores inferiores. Los objetivos de tratamiento consistieron en lograr relajación muscular y promover un posicionamiento condilar ortopédicamente funcional y estable, realizar control vertical para disminuir gap interlabial, alinear líneas medias, mantener clase I molar bilateral, clase I canina bilateral y clase I incisiva, crear overjet y overbite adecuados, con recuperación estética y función del segmento anterior. Debido a eventos adversos durante la etapa de cierre de espacios, la clase molar y canina I no se logró, pero se aseguró mediante ameloplastias positivas la función y estética adecuadas para tener un tratamiento de ortodoncia estable a largo plazo (AU)

The following is a case of a 12-year-old patient, with a history of bruxism, with a mesofacial biotype, lower third of the facial area, muscular hypertonicity in the masseters, a forced labial closure with a 4-millimeter labial incompetence with pain in inferior anterior synoviums. Treatment objectives consisted of achieving muscle relaxation and promoting orthopedically functional and stable condylar positioning, perform vertical control to decrease interlabial gap, align midlines, maintain bilateral molar class I, bilateral canine class I and incisive class I, create adequate overjet and overbite, with aesthetic recovery and function of the anterior segment. Due to adverse events during the closing phase of spaces, the molar and canine I class was not achieved, but positive function and aesthetics were ensured by positive ameloplasties in order to have a long-term stable orthodontic treatment (AU)

MGL1 Receptor Plays a Key Role in the Control of T. cruzi Infection by Increasing Macrophage Activation through Modulation of ERK1/2, c-Jun, NF-κB and NLRP3 Pathways.

Macrophage galactose-C type lectin (MGL)1 receptor is involved in the recognition of Trypanosoma cruzi (T. cruzi) parasites and is important for the modulation of the innate and adaptive immune responses. However, the mechanism by which MGL1 promotes resistance to T. cruzi remains unclear. Here, we show that MGL1 knockout macrophages (MGL1-/- Mφ) infected in vitro with T. cruzi were heavily parasitized and showed decreased levels of reactive oxygen species (ROS), nitric oxide (NO), IL-12 and TNF-α compared to wild-type macrophages (WT Mφ). MGL1-/- Mφ stimulated in vitro with T. cruzi antigen (TcAg) showed low expression of TLR-2, TLR-4 and MHC-II, which resulted in deficient splenic cell activation compared with similar co-cultured WT Mφ. Importantly, the activation of p-ERK1/2, p-c-Jun and p-NF-κB p65 were significantly reduced in MGL1-/- Mφ exposed to TcAg. Similarly, procaspase 1, caspase 1 and NLRP3 inflammasome also displayed a reduced expression that was associated with low IL-ß production. Our data reveal a previously unappreciated role for MGL1 in Mφ activation through the modulation of ERK1/2, c-Jun, NF-κB and NLRP3 signaling pathways, and to the development of protective innate immunity against experimental T. cruzi infection.

Biomedical Properties of Propolis on Diverse Chronic Diseases and Its Potential Applications and Health Benefits.

The use of alternative medicine products has increased tremendously in recent decades and it is estimated that approximately 80% of patients globally depend on them for some part of their primary health care. Propolis is a beekeeping product widely used in alternative medicine. It is a natural resinous product that bees collect from various plants and mix with beeswax and salivary enzymes and comprises a complex mixture of compounds. Various biomedical properties of propolis have been studied and reported in infectious and non-infectious diseases. However, the pharmacological activity and chemical composition of propolis is highly variable depending on its geographical origin, so it is important to describe and study the biomedical properties of propolis from different geographic regions. A number of chronic diseases, such as diabetes, obesity, and cancer, are the leading causes of global mortality, generating significant economic losses in many countries. In this review, we focus on compiling relevant information about propolis research related to diabetes, obesity, and cancer. The study of propolis could generate both new and accessible alternatives for the treatment of various diseases and will help to effectively evaluate the safety of its use.

[A systematic review about the most important attributes of clinical teachers]. / Los atributos de un tutor clínico de excelencia: una revisión sistemática.

Knowing what characterizes an excellent teacher is relevant to guide training, evaluation, and continuous improvement of the clinical teacher. We performed a systematic review using the PRISMA protocol, aiming to identify the attributes of an excellent clinical teacher. MEDLINE, ERIC, ScienceDirect, and Scopus databases were searched for articles published in English and Spanish, between 2007 and 2019. Two independent reviewers extracted and synthesized data from articles that met the PRISMA pre-established criteria. Twelve studies met the inclusion criteria. Of the 106 attributes reported by the studies, 49 (46,2%) were generic. The most frequently mentioned attribute was respectfulness. Forty-six attributes (43,3%) were pedagogical. Feedback and planning were those most frequently mentioned. Eleven attributes (10,3%) were disciplinary and clinical skills was the most mentioned. We conclude that generic and pedagogical dimensions had a greater representation in the literature, in comparison with the disciplinary dimension. This could be explained, considering that having adequate clinical skills is the minimal necessary requisite to become a clinical teacher, but does not make a difference in how their performance is perceived, contrary to the generic and pedagogical dimensions.

Hypoglycaemic and Antioxidant Effects of Propolis of Chihuahua in a Model of Experimental Diabetes.

Propolis is a bee-collected natural product that has been proven to have various bioactivities. This study tested the effects of a Mexican propolis on streptozotocin-induced diabetes mellitus in a murine model. The results showed that an ethanolic extract of propolis of Chihuahua (EEPCh) significantly inhibited increases in blood glucose and the loss of body weight in diabetic mice. EEPCh increased plasma insulin levels in STZ-diabetic mice, whereas, in untreated diabetic mice, there was no detection of insulin. EEPCh had a high antioxidant capacity (SA50 = 15.75 µg/mL), which was directly related to the concentrations of total phenols (314 mg GAE/g of extract) and flavonoids (6.25 mg QE/g of extract). In addition, increased activities of the enzymes superoxide dismutase, catalase, and glutathione peroxidase were observed in diabetic mice treated with EEPCh. Compounds such as pinocembrin, quercetin, naringin, naringenin, kaempferol, acacetin, luteolin, and chrysin were identified by HPLC-MS analysis. This investigation demonstrated that propolis of Chihuahua possesses hypoglycaemic and antioxidant activities and can alleviate symptoms of diabetes mellitus in mice. These effects may be directly related to the chemical composition of propolis, as most of the compounds identified in propolis are reportedly active in terms of the different parameters evaluated in this work.

Protective Effect of Amphipterygium adstringens Extract on Dextran Sulphate Sodium-Induced Ulcerative Colitis in Mice.

Amphipterygium adstringens is an endemic species in Mexico commonly known as "cuachalalate." Healers to treat gastritis, gastric ulcers, and gastrointestinal cancer have traditionally used the bark. We investigated the effects of alcoholic extract of A. adstringens (AaEE) in DSS-induced colitis in mice. The protective effect of AaEE was determined at 200 mg/kg by oral gavage for 10 days. We determine the effect of AaEE on clinical features (disease activity index), antioxidants, anti-inflammatory, and immunomodulatory activities in relation to the activity of SOD, CAT, and GPx, levels of proinflammatory cytokines, and changes both macroscopic and microscopic of the colonic mucosa. AaEE significantly reduced the inflammation of colon and significantly increased SOD and GPx activities. AaEE also significantly decreased TNF-α, IFN-γ, and IL-1ß cytokine levels compared to DSS-treated mice and reduced both infiltration of inflammatory cells and the mucosal damage in colon. The results suggested the protective potential of AaEE in DSS-induced colitis and this might be attributed to its phytochemicals compounds that have been found to induce a wide spectrum of activities such as reduction in oxidative stress, suppression of inflammation, modulating numerous signal transduction pathways, and induction of apoptosis. The findings of this study suggest that AaEE has substantial potential for the treatment of inflammatory colitis.

Evaluation of the medicinal properties of Cyrtocarpa procera Kunth fruit extracts.

BACKGROUND: The fruit of Cyrtocarpa procera is used to treat stomach diseases by people living in San Rafael, Coxcatlan, Puebla. This work investigated the antibacterial, antioxidant, cytotoxic and anti-inflammatory activities of the fruit produced by this species. METHODS: Methanol extract was obtained by maceration. After obtaining the methanol extract (MeOH1), methanol subextract (MeOH2) and hexane (H) were obtained. The antibacterial activities of MeOH1, MeOH2 and H were evaluated through disc-diffusion. The quenching of free radicals was evaluated by decolorizing a methanolic DPPH solution. The cytotoxic activity of MeOH2 was evaluated by in vitro assay system of growth inhibition of human cervical carcinoma cell line (CasKi). The IL-1ß and TNF-α were determined through ELISA in the supernatants of the macrophage cell line (RAW 264.7). The MeOH2 subextract was separated by column chromatography, seventy-three fractions were collected. RESULTS: The Gram-positive and -negative bacteria examined were sensitive to MeOH1 and MeOH2; the MeOH2 was bactericidal toward Staphyloccocus aureus (MIC = 4 mg/mL) and Vibrio cholera (MIC = 4 mg/mL). The MeOH2 inhibited the DPPH radical (SC50 = 69.7 µg/mL), but a cytotoxicity assay revealed that the extract is not toxic according to the National Cancer Institute (LD50 = 22.03 µg/mL). The production of proinflammatory cytokines (IL- 1ß and TNF- α) by LPS- stimulated macrophages was reduced after the treatments. The methanol extract contained various organic acids, such as citric acid, palmitic acid and α- linoleic acid. CONCLUSIONS: The fruits of Cyrtocarpa procera are employed to treat ailments such as diarrhea, in this study were demonstrated some biological activities involved in a bacterial infection. This is the first research about of the medicinal properties of C. procera fruit.

Competencias para la enfermera/o en el ámbito de gestión y administración: desafíos actuales de la profesión / Skills for Nurses in the Field of Management and Administration: Contemporary Challenges to the Profession / Competências para a enfermeira/o no âmbito de gestão e administração: desafios atuais da profissão

Las competencias laborales de enfermería permiten disminuir inequidades, acceso limitado a los servicios y favorecen una atención segura y de calidad. La formación de enfermeras/os es fundamental en la composición y dinámica de la fuerza de trabajo en enfermería, la calidad y pertinencia de los cuidados y el desarrollo de la capacidad institucional en salud. Objetivo: responder dos interrogantes: ¿Cuáles son los requerimientos actuales para el/la enfermero/a en el ámbito de la gestión y administración?, y ¿cuáles son las competencias de gestión de enfermería más importantes y su relación con la gestión de cuidado? Método: revisión de la literatura que parte con una exploración de campo desde los contextos y desafíos actuales de la profesión. La búsqueda bibliográfica se realizó en las bases de datos Cochrane Library, Lilacs, CINHAL, Dialnet, Universidad de la Rioja, ProQuest, Web of Science, Science Direct, PubMed, Business Source Premier, SciELO, Scopus. Se encontraron 4.697 artículos. Precisando la búsqueda se seleccionaron 51 artículos y documentos técnicos. Resultados: los estudios que priorizan las competencias de gestión coinciden en colocar entre las más importantes: comunicación, trabajo en equipo, resolución de conflictos y habilidades interpersonales y de liderazgo. En liderazgo priorizan dominio personal, efectividad interpersonal, gestión financiera y de recursos humanos. Conclusiones: las habilidades de gestión y liderazgo se deben basar en conocimientos sólidos y en la experiencia. Asimismo, la concepción de gestión y liderazgo ocupa un lugar complementario al rol de cuidado que tiene la enfermera/o. El liderazgo transformacional y relacional son necesarios para mejorar la satisfacción de las/os enfermeras/os.

The job skills involved in nursing make it possible to reduce inequalities and limited access to services, and to support safe and quality care. The training nurses receive is fundamental to the composition and dynamics of the nursing work force, the quality and appropriateness of nursing care, and the development of institutional capacity in the health sector. Objective: The study was designed to answer two questions: What are the current requirements for nurses in the field of management and administration; and what nursing management skills are most important and how do they relate to health care management? Method: The literature review began by exploring the field in terms of current contexts and challenges to the profession. The bibliographic search involved several the databases; namely, the Cochrane Library, Lilacs, CINAHL, Dialnet, the University of La Rioja, ProQuest, Web of Science, ScienceDirect, PubMed, Business Source Premier, SciELO and Scopus. In all, 4,697 articles were found. When the search was narrowed, 51 technical papers were selected. Results: The studies that prioritize management skills coincide in that the most important ones are: communication, teamwork, conflict resolution, and interpersonal and leadership skills. As for leadership, the priority is on personal mastery, interpersonal effectiveness, financial management and human resources. Conclusions: Management and leadership skills must be based on sound knowledge and experience. Moreover, the concept of management and leadership is complementary to the role of nurses in providing care. Transformational and relational leadership are needed to improve the satisfaction of nurses.

As competências laborais de enfermagem permitem diminuir inequidades, acesso limitado aos serviços e favorecem um atendimento seguro e de qualidade. A formação de enfermeiras/os é fundamental na composição e dinâmica da força de trabalho em enfermagem, na qualidade e pertinência dos cuidados e no desenvolvimento da capacidade institucional em saúde. Objetivo: responder a duas interrogantes: Quais são os requerimentos atuais para a/o enfermeira/o no âmbito da gestão e da administração? Quais são as competências de gestão de enfermagem mais importantes e sua relação com a gestão de cuidado? Método: revisão da literatura que parte com uma exploração de campo a partir dos contextos e desafios atuais da profissão. A busca bibliográfica foi realizada nas bases de dados Cochrane Library, Lilacs, CINHAL, Dialnet, Universidad de la Rioja, ProQuest, Web of Science, Science Direct, PubMed, Business Source Premier, SciELO, Scopus. Encontraram-se 4.697 artigos. Precisando a busca, selecionaram-se 51 artigos e documentos técnicos. Resultados: os estudos que priorizam as competências de gestão coincidem em colocar entre as mais importantes: comunicação, trabalho em equipe, resolução de conflitos e habilidades interpessoais e liderança. Em liderança, priorizam domínio pessoal, efetividade interpessoal, gestão financeira e de recursos humanos. Conclusões: as habilidades de gestão e liderança devem ser baseadas em conhecimentos sólidos e na experiência. Além disso, a concepção de gestão e liderança ocupa um lugar complementar ao papel de cuidado que a/o enfermeira/o tem. A liderança transformacional e relacional são necessárias para melhorar a satisfação das/os enfermeiras/os.

Desynchronization/synchronization of parasagittal EEG rhythms during habituation to photostimulation in adults.

INTRODUCTION: Learning by habituation implies a gradual diminution of the organism's responses to non-relevant stimuli. These responses, resulting from electrical oscillations of the brain, can be analyzed through quantitative electroencephalography (qEEG). OBJECTIVE: To characterize the absolute power (AP) in the range of delta (δ), theta (θ), alpha (α), beta (ß) in cortical parasagittal regions during habituation to photostimulation (RPh). MATERIAL AND METHODS: We studied 81 undergraduate students. The EEG was recorded in a Nicolet; awake subjects with closed eyes were photostimulated (5 Hz for 2 s, 20 times, RPh). The UAMI/Yáñez program identifies the RPh signal, chooses and collects 2-sec samples before (Pre) and during RPh, and instruments the Welch periodogram, which integrates the absolute power (AP) of δ, θ, α, and ß. We calculated the average AP (AAP) in Pre and RPh per frequency and lead. AAP differences were assessed with non-parametric tests. Linear regression was used to plot the AAPs of each Pre and each RPh sample, representing the resulting slope with its statistical significance. RESULTS: RPh increased the AAP of δ in frontal and frontocentral leads of both hemispheres, and its slopes were ascendant. AAP of θ increased in fronto-frontal and diminished in the other three leads, its slopes were ascendant in right central parietal and parieto-occipital leads. AAP of α increased in fronto-frontal leads, did not change in fronto-central, and diminished in the other leads; its slopes were descendent in Pre and ascendant in RPh in both hemispheres. AAP of ß increased in the four leads; in Pre, ß slopes were descendent in parieto-occipital leads of both hemispheres. During RPh, δ slopes were ascendant in right parieto-central and in both parieto-occipital leads. CONCLUSION: The progressive diminution of alpha's desynchronization, which ends in synchronization, is probably due to hyperpolarization of neuronal membranes and represents habituation. This is complemented with synchronization of the delta rhythm in anterior cortical areas and of theta and beta in areas of the right hemisphere.

[Absolute power of cortical oscillations and their topographical distribution in a sample of young adults during resting wakefulness and unspecific attention]. / Potencia absoluta de oscilaciones corticales y su distribución topográfica en una muestra de adultos jóvenes en vigilia inactiva y en atención inespecífica.

INTRODUCTION: The EEG records neuronal membrane potential oscillations that depend on the morpho-functional characteristics of the membrane and of modifications by postsynaptic excitatory (PSEP) and inhibitory (PSIP) potentials. The quantitative EEG (qEEG) measures the absolute power (AP) of oscillations separated in frequencies, resulting from the interaction among subcortical-cortical-subcortical ensembles. The hypothesis is that neuronal networks function at a given frequency and that their APs are codes that, by becoming synchronized in diverse ensembles, generate behavior. OBJECTIVE: To establish the spectral power of cortical oscillations under diverse study paradigms and in different populations. In particular, to identify the AP and topographical distribution of four cerebral frequency bands under resting wakefulness and activation, and to integrate results into a database to establish comparison standards. MATERIAL AND METHODS: Undergraduate students, average age of 20.6 +/- 2.6 years, who participated voluntarily in the study. Recordings were made with a Nicolet EEG. We chose, in the first stage, closed eyes (CE) three samples of 12 s each. In the second stage, we chose pairs of 6 s samples, first with CE and then with OE. For their analysis, we applied the Welch periodogram and we plotted the average AP (AAP) and standard deviation (SD) of delta, theta, alpha, and beta per lead. Differences were compared through non-parametric tests (Wilcoxon and Dunnett T3); setting statistical significance at a = 0.05. RESULTS: Average APs of each frequency band differ significantly in intensity and topographic distribution generating a profile of each rhythm. When opening the eyes, rhythms desynchronized significantly at different intensities in the diverse leads, except for beta in the left fronto-frontal lead. DISCUSSION: Results indicate the existence of cortical ensembles that synchronize at a determined frequency and are modified by visual stimulation, indicating the effects of the subcortico-cortical circuits. The integrated database provides comparison standards to support diagnoses and treatments.