ABSTRACT
Left ventricular rupture resulting in death has been reported to be a complication of percutaneous mitral commissurotomy. We report a 71-year-old man in whom a left ventricular rupture occurred during percutaneous mitral commissurotomy and resulted in hemodynamic collapse due to acute cardiac tamponade. The patient was stabilized using percutaneously instituted cardiopulmonary bypass support with subsequent repair of the left ventricle and successful mitral valve replacement. Three months later this patient remains in New York Heart Class I.
Subject(s)
Balloon Occlusion , Cardiopulmonary Bypass/methods , Catheterization/adverse effects , Heart Injuries/etiology , Mitral Valve Stenosis/therapy , Aged , Heart Injuries/therapy , Heart Ventricles/injuries , Humans , MaleABSTRACT
A patient with significant left anterior descending coronary disease is presented who developed significant ST segment elevation and depression at different times under similar testing conditions. Currently proposed explanations for exercise-induced ST segment elevation are discussed. This patient likely represents a case of spasm superimposed on significant obstructive disease, so-called mixed angina.
Subject(s)
Coronary Disease/physiopathology , Electrocardiography , Physical Exertion , Aged , Heart Rate , Humans , MaleABSTRACT
The effect of a residual coronary artery stenosis on size of myocardial infarction was studied in an open-chest canine preparation of coronary occlusion and reperfusion. Eighteen male mongrel dogs (16 to 26 kg) underwent left thoracotomy under general anesthesia; the circumflex artery was instrumented with a hydraulic cuff occluder, a screw clamp, and an electromagnetic flow probe. Animals were randomized to one of three groups: group I (n = 6) had a 6 hr circumflex occlusion, group II (n = 6) had a 2 hr occlusion followed by 4 hr of partial reperfusion through a residual stenosis adjusted to approximately 30% of baseline flow, and group III (n = 6) had full reperfusion for 4 hr after a 2 hr occlusion. Zones of risk, infarction, and no reflow were defined by staining with Evans blue, triphenyl tetrazolium chloride, and fluorescein, respectively. At 6 hr the hearts were excised and areas of risk, infarction, no reflow, and hemorrhage were determined by planimetry of serial transverse heart slices (5 mm thick). Infarction as a percent of the risk area was 96 +/- 1% in group I, 90 +/- 2% in group II, and 79 +/- 4% in group III (p less than .001), and the differences between each of the groups were significant. Gross hemorrhage was seen in none of the six dogs in group I, two of the six in group II, and five of the six in group III, but did not affect infarct size. We conclude that residual stenoses may exert a deleterious effect on the outcome of coronary reperfusion.(ABSTRACT TRUNCATED AT 250 WORDS)
Subject(s)
Arterial Occlusive Diseases/physiopathology , Coronary Circulation , Myocardial Infarction/pathology , Animals , Blood Flow Velocity , Blood Pressure , Dogs , Electrocardiography , Heart Rate , Hemorrhage/pathology , Male , Myocardial Infarction/physiopathology , Myocardial Infarction/therapy , Necrosis , Perfusion , RiskABSTRACT
We have described a patient who had Candida albicans suppurative thrombophlebitis at the site of an indwelling intravenous catheter. The microbial etiology was established by needle aspiration of the venipuncture site, affording rapid and accurate identification of the infecting organism and providing prompt institution of therapy. Phlebectomy and a brief course of amphotericin B prevented further dissemination of the infection.
