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1.
Indian J Pathol Microbiol ; 64(3): 568-570, 2021.
Article in English | MEDLINE | ID: mdl-34341275

ABSTRACT

In the case of single fetal demise in a twin gestation, the fate of the dead twin, surviving twin, and mother depend on the exact time of fetal demise. The dead twin may "vanish" in a first trimester death; form a mummified "fetus papyraceus" due to mechanical compression in the second trimester or show changes of maceration in the third trimester. Hematological complications in the mother and neurological complications in the surviving twin may ensue in later trimester deaths. We report a unique case of an undiagnosed fetus papyraceus incidentally detected in an otherwise normal placenta. Identification of such cases is essential due to the occurrence of severe complications in some of the cases, medicolegal implications for the caregivers, and to improve the understanding of embryological development and fetal demise in twin or multiple gestations.


Subject(s)
Fetal Death , Placenta/pathology , Twins , Adult , Female , Histological Techniques , Humans , Pregnancy , Pregnancy Complications
2.
Indian J Pathol Microbiol ; 64(1): 91-95, 2021.
Article in English | MEDLINE | ID: mdl-33433415

ABSTRACT

CONTEXT: Twelve-year retrospective study of surgically excised umbilical lesions received for histopathology in a pediatric tertiary care hospital. AIMS: To study histopathology of the umbilical lesions and review pertinent literature on the embryological basis of these lesions. SUBJECTS AND METHODS: We reviewed cases of umbilical lesions and classified them as "developmental" and "others." Developmental cases were sub-classified based on the mechanism as those due to defect in the closure of body wall, defect in the closure of the umbilical ring, persistence of embryonic remnants, or failure of epithelization. Persistent embryonic remnants were subdivided into fistula, sinus, and cyst. Histology of all the cases was studied and the different types of tissue in omphalomesenteric ducts (OMD) remnants were identified. STATISTICAL ANALYSIS USED: Descriptive statistics were used as required. RESULTS: Seventy-one cases in the age range of 1 day to 13 years were studied and male preponderance was noted. The developmental lesions included 4 omphalocele sacs with dense acute inflammation, 2 umbilical hernial sacs with fibrocollagenous tissue, 30 OMD remnants, 10 allantoic duct remnants, 19 umbilical granulomas, and 2 cases showing more than one developmental mechanism. Four cases were classified as "others" including 3 epidermal inclusion cysts and 1 skin tag. Among OMD remnants, sinuses (arising from the distal tract) were found to be the most common. Histological examination of the OMD remnants showed enteric (18), enteric and gastric (5), colonic (4), enteric and colonic (2), and pancreatic and enteric and gastric mucosae (1). CONCLUSION: Accurate diagnosis is essential for definite treatment of these lesions.


Subject(s)
Histological Techniques , Umbilicus/pathology , Adolescent , Child , Child, Preschool , Cysts , Female , Humans , Infant , Infant, Newborn , Inflammation , Male , Retrospective Studies , Tertiary Care Centers/statistics & numerical data , Umbilicus/anatomy & histology , Vitelline Duct/pathology
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