1.
J Org Chem
; 84(11): 7488-7494, 2019 Jun 07.
Article
in English
| MEDLINE
| ID: mdl-31066282
ABSTRACT
A new protocol for the alkylation of aromatic amines has been described using alcohols in the presence of SmI2 as a catalyst with the generation of water as the sole byproduct. The reaction proceeds under MW conditions and selectively generates monoalkylated amines. This protocol features a broad substrate scope and good functional-group tolerance with moderate to high yields.