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Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
; 149(2): 237-41, 2005 Dec.
Article
in English
| MEDLINE
| ID: mdl-16601762
ABSTRACT
Peroxisome proliferator-activated receptors (PPARs) are subgroups of nuclear hormonal receptors of transcripting factors mostly found in adipose tissue. They are described as important regulators of lipid and saccharide metabolism including insulin sensitivity; therefore they are taken as marker of metabolic syndrome. Their synthetic ligands could be used as drugs for insulin resistance and type 2 diabetes mellitus.