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Chem Commun (Camb) ; 50(85): 12863-6, 2014 Nov 04.
Article in English | MEDLINE | ID: mdl-25211167

ABSTRACT

The SmI2-H2O reagent system mediates challenging 5-exo/6-exo lactone radical cascade cyclisations that deliver carbo[5.4.0]bicyclic motifs in a diastereoselective, one-pot process that establish two new carbocyclic rings and four stereocentres.


Subject(s)
Alkadienes/chemistry , Iodides/chemistry , Lactones/chemistry , Samarium/chemistry , Bridged Bicyclo Compounds/chemistry , Crystallography, X-Ray , Cyclization , Indicators and Reagents , Models, Molecular , Oxidation-Reduction , Stereoisomerism , Water/chemistry
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