ABSTRACT
AIM: This study aimed to identify the postoperative histological features affecting the prognosis of patients with early-stage cervical cancer who underwent open radical hysterectomy. METHODS: This retrospective study enrolled 374 patients with pT1a, 1b1 and 2a1 early-stage cervical cancer who underwent open radical hysterectomy between 2001 and 2018. Survival outcomes were analyzed by Kaplan-Meier method and compared with log-rank test. Using the Cox proportional hazards regression test, we conducted a multivariate analysis for disease-free survival and overall survival. RESULTS: Others histology, including other epithelial tumors and neuroendocrine tumors, had a significantly worse prognosis in both disease-free survival and overall survival than those of squamous cell carcinoma and adenocarcinoma (hazard ratio, 4.37 and 11.76; P = 0.006 and P = 0.002, respectively), along with lymph node metastasis (hazard ratio, 2.99 and 7.03; P = 0.009 and P = 0.001, respectively). CONCLUSION: Others histology including adenosquamous carcinoma had a poor prognosis in early-stage cervical cancer as with high-risk factors.
Subject(s)
Carcinoma, Adenosquamous , Uterine Cervical Neoplasms , Carcinoma, Adenosquamous/pathology , Carcinoma, Adenosquamous/surgery , Female , Humans , Hysterectomy , Neoplasm Staging , Prognosis , Retrospective Studies , Risk Factors , Uterine Cervical Neoplasms/pathology , Uterine Cervical Neoplasms/surgeryABSTRACT
Ovarian epidermoid cyst, an extremely rare tumor occurring mostly in older females, is lined by mature stratified squamous epithelium and distinguishable from mature teratoma by the absence of skin adnexae and other tissues. In imaging, these tumors resemble solid tumors, necessitating most patients to undergo oophorectomy to verify malignancy. We herein present the case of an ovarian epidermoid cyst in a pregnant woman who underwent laparoscopic cystectomy after delivery with preserved ovarian function. To the best of our knowledge, this is the first case report of an ovarian epidermoid cyst that was detected during pregnancy and treated with laparoscopic cystectomy. Preservation of ovarian function and application of minimally invasive surgery should be strongly considered in young patients with ovarian epidermoid cysts.
