1.
Phytochemistry
; 76: 98-105, 2012 Apr.
Article
in English
| MEDLINE
| ID: mdl-22277737
ABSTRACT
Six flavonoids named cryptogiones A-F, and nine known compounds were isolated from an ethanol extract of stems of Cryptocaryachingii. The structures of the compounds were elucidated by interpretation of comprehensive spectroscopic data and X-ray analysis. A majority of these flavonoids contained an acetic acid/lactone moiety, a possible taxonomic marker. Anti-inflammatory effects of the compounds were evaluated using in vitro assays. At 20 µM concentration, three compounds significantly inhibited TNFα-induced NF-кB activation and LPS-induced IL-1ß expression.