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1.
Research (Wash D C) ; 6: 0226, 2023.
Article in English | MEDLINE | ID: mdl-37746659

ABSTRACT

Asia stands out as a priority for urgent biodiversity conservation due to its large protected areas (PAs) and threatened species. Since the 21st century, both the highlands and lowlands of Asia have been experiencing the dramatic human expansion. However, the threat degree of human expansion to biodiversity is poorly understood. Here, the threat degree of human expansion to biodiversity over 2000 to 2020 in Asia at the continental (Asia), national (48 Asian countries), and hotspot (6,502 Asian terrestrial PAs established before 2000) scales is investigated by integrating multiple large-scale data. The results show that human expansion poses widespread threat to biodiversity in Asia, especially in Southeast Asia, with Malaysia, Cambodia, and Vietnam having the largest threat degrees (∼1.5 to 1.7 times of the Asian average level). Human expansion in highlands induces higher threats to biodiversity than that in lowlands in one-third Asian countries (most Southeast Asian countries). The regions with threats to biodiversity are present in ∼75% terrestrial PAs (including 4,866 PAs in 26 countries), and human expansion in PAs triggers higher threat degrees to biodiversity than that in non-PAs. Our findings provide novel insight for the Sustainable Development Goal 15 (SDG-15 Life on Land) and suggest that human expansion in Southeast Asian countries and PAs might hinder the realization of SDG-15. To reduce the threat degree, Asian developing countries should accelerate economic transformation, and the developed countries in the world should reduce the demands for commodity trade in Southeast Asian countries (i.e., trade leading to the loss of wildlife habitats) to alleviate human expansion, especially in PAs and highlands.

2.
Sensors (Basel) ; 23(18)2023 Sep 20.
Article in English | MEDLINE | ID: mdl-37766035

ABSTRACT

Multi-UAV systems have been widely used in reconnaissance, disaster relief, communication, and other fields. However, many dynamic events can cause a partial failure of the original mission during the mission execution process, in which case task reassignment should be carried out. How to reassign resources and tasks in multi-dynamic, multi-target, and multi-constraint events becomes a core issue in the enhancement of combat efficiency. This paper establishes a model of multi-UAV cooperative reconnaissance task reassignment that comprehensively considers various dynamic factors such as UAV performance differences, size of target areas, and time window constraints. Then, a two-stage distributed task assignment algorithm (TS-DTA) is presented to achieve multi-task reassignment in dynamic environments. Finally, this paper verifies the effectiveness of the TS-DTA algorithm through simulation experiments and analyzes its performance through comparative experiments. The experimental results show that the TS-DTA algorithm can efficiently solve the task reassignment problem in dynamic environments while effectively reducing the communication burden of UAV formations.

3.
IEEE Trans Image Process ; 31: 2584-2597, 2022.
Article in English | MEDLINE | ID: mdl-35286258

ABSTRACT

Traditional image feature matching methods cannot obtain satisfactory results for multi-modal remote sensing images (MRSIs) in most cases because different imaging mechanisms bring significant nonlinear radiation distortion differences (NRD) and complicated geometric distortion. The key to MRSI matching is trying to weakening or eliminating the NRD and extract more edge features. This paper introduces a new robust MRSI matching method based on co-occurrence filter (CoF) space matching (CoFSM). Our algorithm has three steps: (1) a new co-occurrence scale space based on CoF is constructed, and the feature points in the new scale space are extracted by the optimized image gradient; (2) the gradient location and orientation histogram algorithm is used to construct a 152-dimensional log-polar descriptor, which makes the multi-modal image description more robust; and (3) a position-optimized Euclidean distance function is established, which is used to calculate the displacement error of the feature points in the horizontal and vertical directions to optimize the matching distance function. The optimization results then are rematched, and the outliers are eliminated using a fast sample consensus algorithm. We performed comparison experiments on our CoFSM method with the scale-invariant feature transform (SIFT), upright-SIFT, PSO-SIFT, and radiation-variation insensitive feature transform (RIFT) methods using a multi-modal image dataset. The algorithms of each method were comprehensively evaluated both qualitatively and quantitatively. Our experimental results show that our proposed CoFSM method can obtain satisfactory results both in the number of corresponding points and the accuracy of its root mean square error. The average number of obtained matches is namely 489.52 of CoFSM, and 412.52 of RIFT. As mentioned earlier, the matching effect of the proposed method was significantly greater than the three state-of-art methods. Our proposed CoFSM method achieved good effectiveness and robustness. Executable programs of CoFSM and MRSI datasets are published: https://skyearth.org/publication/project/CoFSM/.

4.
J Virol ; 92(13)2018 07 01.
Article in English | MEDLINE | ID: mdl-29669832

ABSTRACT

Orthologs of the herpes simplex virus (HSV) UL16 gene are conserved throughout the Herpesviridae Because of this conservation, one might expect that the proteins perform similar functions for all herpesviruses. Previous studies on a UL16-null mutant derived from HSV-2 strain 186 revealed a roughly 100-fold replication defect and a critical role for UL16 in the nuclear egress of capsids. These findings were in stark contrast to what has been observed with UL16 mutants of HSV-1 and pseudorabies virus, where roughly 10-fold replication deficiencies that were accompanied by defects in the secondary envelopment of cytoplasmic capsids were reported. One possible explanation for this discrepancy is that HSV-2 strain 186 is not representative of the HSV-2 species. To address this possibility, multiple UL16-null mutants were constructed in multiple HSV-2 and HSV-1 strains by CRISPR/Cas9 mutagenesis, and their phenotypes were characterized side by side. This analysis showed that all the HSV-2 UL16 mutants had 50- to 100-fold replication deficiencies that were accompanied by defects in the nuclear egress of capsids, as well as defects in the secondary envelopment of cytoplasmic capsids. By contrast, most HSV-1 UL16 mutants had 10-fold replication deficiencies that were accompanied by defects in secondary envelopment of cytoplasmic capsids. These findings indicated that UL16 has HSV species-specific functions. Interestingly, HSV-1 UL16 could promote the nuclear egress of HSV-2 UL16-null strains, suggesting that, unlike HSV-1, HSV-2 lacks an activity that can promote nuclear egress in the absence of UL16.IMPORTANCE HSV-2 and HSV-1 are important human pathogens that cause distinct diseases in their hosts. A complete understanding of the morphogenesis of these viruses is expected to reveal vulnerabilities that can be exploited in the treatment of HSV disease. UL16 is a virion structural component that is conserved throughout the Herpesviridae and functions in virus morphogenesis; however, previous studies have suggested different roles for UL16 in the morphogenesis of HSV-2 and HSV-1. This study sought to resolve this apparent discrepancy by analyzing multiple UL16 mutant viruses derived from multiple strains of HSV-2 and HSV-1. The data indicate that UL16 has HSV species-specific functions, as HSV-2 has a requirement for UL16 in the escape of capsids from the nucleus whereas both HSV-2 and HSV-1 require UL16 for final envelopment of capsids at cytoplasmic membranes.


Subject(s)
Herpes Simplex/virology , Herpesvirus 1, Human/physiology , Herpesvirus 2, Human/physiology , Mutation , Viral Proteins/metabolism , Virus Replication , Animals , Chlorocebus aethiops , Humans , Species Specificity , Vero Cells , Viral Proteins/genetics
5.
PLoS One ; 7(7): e41419, 2012.
Article in English | MEDLINE | ID: mdl-22848489

ABSTRACT

A number of studies have suggested that many properties of brain activity can be understood in terms of critical systems. However it is still not known how the long-range susceptibilities characteristic of criticality arise in the living brain from its local connectivity structures. Here we prove that a dynamically critically-poised model of cortex acquires an infinitely-long ranged susceptibility in the absence of input. When an input is presented, the susceptibility attenuates exponentially as a function of distance, with an increasing spatial attenuation constant (i.e., decreasing range) the larger the input. This is in direct agreement with recent results that show that waves of local field potential activity evoked by single spikes in primary visual cortex of cat and macaque attenuate with a characteristic length that also increases with decreasing contrast of the visual stimulus. A susceptibility that changes spatial range with input strength can be thought to implement an input-dependent spatial integration: when the input is large, no additional evidence is needed in addition to the local input; when the input is weak, evidence needs to be integrated over a larger spatial domain to achieve a decision. Such input-strength-dependent strategies have been demonstrated in visual processing. Our results suggest that input-strength dependent spatial integration may be a natural feature of a critically-balanced cortical network.


Subject(s)
Evoked Potentials/physiology , Models, Neurological , Nerve Net/physiology , Neural Pathways/physiology , Visual Cortex/physiology , Visual Perception/physiology , Animals , Cats , Humans , Macaca
6.
J Nanosci Nanotechnol ; 7(12): 4322-32, 2007 Dec.
Article in English | MEDLINE | ID: mdl-18283810

ABSTRACT

The present work examines the behavior of multiwall carbon nanotubes (MWCNT) inside AC electric fields created by three-dimensional electrodes. The response of carbon nanotubes stably suspended in water with the aid of a nonionic surfactant is monitored by combining microscopic observations with on-line measurements of the suspension resistivity. It is found that polarization effects induced by the externally applied AC electric field on MWCNTs can cause their unidirectional orientation and end-to-end contact that result in formations of spatially distributed, long-range, three-dimensional and electrically conducting structures that span the entire gap between the electrodes. The length of the formed structures, which in the present case was approximately 30 times larger than that of an individual carbon nanotube, can be controlled by adjusting the spacing between the electrodes. The influence of main experimental parameters, namely, MWCNT concentration, applied voltage, AC field frequency, and electrode surface topography on the suspension behavior is experimentally examined. Results are demonstrated for applied voltage values, AC field frequencies, and carbon nanotube concentrations in the range 4-40 Vptp, 10 Hz-5 MHz, and 0.001-2.0 wt%, respectively. While higher electric field strengths accelerate the formation of aligned structures, higher frequency values were found to result in suspensions that exhibit smaller electrical resistivity. Carbon nanotube dispersions exposed to an AC electric field exhibit a 100-fold or more decrease in their electrical resistivity, even when carbon nanotube concentrations as low as 0.005 wt% are used.

7.
J Am Chem Soc ; 127(44): 15358-9, 2005 Nov 09.
Article in English | MEDLINE | ID: mdl-16262385

ABSTRACT

Reported is a novel and simple method for the preparation of polymer spheres bearing hemispherical surface bumps where one type of polymer chains concentrates. The method is used to produce spheres with a diameter between approximately 30 and approximately 500 nm. Spheres with chain-segregated bumpy surfaces may find applications in drug delivery and other areas.

8.
J Am Chem Soc ; 126(32): 10059-66, 2004 Aug 18.
Article in English | MEDLINE | ID: mdl-15303882

ABSTRACT

Different nanotubes were prepared from two triblock copolymers. Chemistry was performed on the nanotubes so that one type contained amino terminal groups and the other bore carboxyl terminal groups. The amino and carboxyl groups were reacted by amidization to join the nanotubes head to tail to yield nanotube multiblocks. The block copolymer nanotube multiblocks (CONATUBLOCs) may be viewed as a macroscopic counterpart of block copolymers. Like block copolymers, the different blocks of the CONATUBLOCs segregated from one another not only in a block-selective solvent mixture but also in the solid state.

9.
Langmuir ; 20(11): 4677-83, 2004 May 25.
Article in English | MEDLINE | ID: mdl-15969181

ABSTRACT

A polystyrene-block-polyisoprene (PS-b-PI) sample with 130 styrene and 370 isoprene units was synthesized and characterized. The diblock formed mostly cylindrical micelles in N,N-dimethylacetamide with a PI core and a PS corona. The PI core of the micelles was cross-linked by S2Cl2 to yield nanofibers. The nanofibers were shortened by ultrasonication to yield fractions withweight-average length (Lw) between approximately 900 and approximately3400 nm. Transmission electron microscopy and light scattering were used to characterize the fractions. The zero-shear intrinsic viscosity data [eta] of the fractions were obtained in tetrahydrofuran (THF), THF/N,N-dimethylformamide (DMF), and THF/cyclohexane (CHX), where THF is a good solvent for both the corona and the core, DMF solubilizes only the corona, and CHX is a theta solvent for the corona chains at 34.5 degrees C. The [eta] data of the fractions were treated by the Bohdanecky method derived from the Yamakawa-Fujii-Yoshizaki (YFY) theory for wormlike polymer chains and yielded the persistence length lP and the hydrodynamic diameters dh for the nanofibers. The reasonable dh values and the reasonable trend of dh variation with solvent quality change establish unambiguously the validity of YFY theory.

10.
J Am Chem Soc ; 125(46): 14039-45, 2003 Nov 19.
Article in English | MEDLINE | ID: mdl-14611240

ABSTRACT

Triblock copolymer nanotubes bearing end-exposed poly(acrylic acid) or PAA core chains were prepared. The exposed PAA chains were reacted by amidization with a large excess of polystyrene spacer chains possessing amino end groups or amino-containing end blocks to graft the spacer chains. The amino groups at the other end of the spacer chains were then reacted with nanospheres bearing surface carboxyl groups to connect the nanotubes to nanospheres. The products from such a coupling reaction ranged from multiarm adduct to surfactant- and dumbbell-like objects. Product control using different strategies was explored. The products may have interesting properties and applications.

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