Global research trends and hotspots for leukocyte cell-derived chemotaxin-2 from the past to 2023: a combined bibliometric review.

Leukocyte cell-derived chemotaxin-2 (LECT2) is an important cytokine synthesized by liver. Significant research interest is stimulated by its crucial involvement in inflammatory response, immune regulation, disease occurrence and development. However, bibliometric study on LECT2 is lacking. In order to comprehend the function and operation of LECT2 in human illnesses, we examined pertinent studies on LECT2 investigation in the Web of Science database, followed by utilizing CiteSpace, VOSview, and Scimago Graphica for assessing the yearly quantity of papers, countries/regions involved, establishments, authors, publications, citations, and key terms. Then we summarized the current research hotspots in this field. Our study found that the literature related to LECT2 has a fluctuating upward trend. "Angiogenesis", "ALECT2", "diagnosis", and "biliary atresia" are the current investigative frontiers. Our findings indicated that liver diseases (e.g. liver fibrosis and hepatic cell carcinoma), systemic inflammatory disease, and amyloidosis are the current research focus of LECT2. The current LECT2 research outcomes are not exceptional. We hope to promote the scientific research of LECT2 and exploit its potential for clinical diagnosis and treatment of related diseases through a comprehensive bibliometric review.

Enhanced Thermoelectric Performance in High Entropy Alloys Sn0.25Pb0.25Mn0.25Ge0.25Te.

Entropy is a physical quantity gauging the degree of chaos in the system. High entropy alloying is thus an effective strategy to reduce the lattice thermal conductivity of the thermoelectric materials. In this paper, PbTe, GeTe, and MnTe are coalloyed with SnTe to form a single-phase solid solution. Because of the inclusion of various elements at the cationic (Sn2+) site, the configurational entropy increases, and the phonon scattering is strongly enhanced, leading to a reduced lattice thermal conductivity. In addition, the Seebeck coefficient is improved because of the band modification via this coalloying. Ga is then further doped to optimize the carrier concentration to ∼5.7 × 1020 cm-3 and reduce the room-temperature lattice thermal conductivity to ∼0.6 W m-1 K-1. Finally, a high peak ZT value of ∼1.52 at 823 K and an average ZT value ∼1.0 from 323 to 823 K were obtained in Ga0.025(Sn0.25Pb0.25Mn0.25Ge0.25)0.975Te.