ABSTRACT
A 55-year-old male patient with hepatitis B-related liver cirrhosis was found to have advanced hepatocellular carcinoma. His AFP was initially 9828 microg/L and rapidly dropped to 5597 microg/L in ten days after oral sorafenib treatment. However, he developed acute renal failure, hyperkalemia, and hyperuricemia 30 d after receiving the sorafenib treatment. Tumor lysis syndrome was suspected and intensive hemodialysis was performed. Despite intensive hemodialysis and other supportive therapy, he developed multiple organ failure (liver, renal, and respiratory failure) and metabolic acidosis. The patient expired 13 d after admission.
Subject(s)
Benzenesulfonates/adverse effects , Carcinoma, Hepatocellular/drug therapy , Liver Neoplasms/drug therapy , Protein Kinase Inhibitors/adverse effects , Pyridines/adverse effects , Tumor Lysis Syndrome/etiology , Carcinoma, Hepatocellular/pathology , Fatal Outcome , Humans , Liver Neoplasms/pathology , Male , Middle Aged , Niacinamide/analogs & derivatives , Phenylurea Compounds , Sorafenib , Tumor Lysis Syndrome/drug therapyABSTRACT
Primary sarcomas of the pulmonary vein are extremely rare. Although myxomas are the most common intracavitary tumor of the left atrium, some findings should alert the clinician to the probability of malignancy. A 28-year-old woman developed hemoptysis, night fever, generalized malaise, anorexia and weight loss for 2 months, with progressive dyspnea for 2 weeks. She was preoperatively diagnosed as left atrial myxoma with a concurrent right lower lung tumor.
Subject(s)
Lung Neoplasms/complications , Myxoma/diagnosis , Myxosarcoma/complications , Myxosarcoma/diagnosis , Adult , Diagnosis, Differential , Female , Heart Atria/pathology , Humans , Pulmonary Veins/pathologyABSTRACT
Fibroepithelial polyps causing ureteropelvic junction obstruction are rarely reported in the pediatric age group. We report a 9-year-old boy who had ureteropelvic junction obstruction that proved to be owing to benign fibroepithelial polyps. Intravenous pyelography showed hydronephrosis with filling defects at the left ureteropelvic junction. Operative exploration revealed several finger-like polypoid neoplasms obstructing the lumen. The involved segment was resected and a dismembered pyeloplasty was performed. Fibroepithelial polyps were diagnosed by histology. The clinical imaging findings, features and methods of surgical treatment of this rare lesion are discussed.
