ABSTRACT
In the title compound, C(11)H(15)ClN(6)O(4)S, which belongs to the neonicotinoid class of insecticidally active heterocyclic compounds, the six-membered triazine ring adopts an opened envolope conformation. The planar nitro imine group [dihedral angle between nitro and imine groups = 1.07â (7)°] and the thia-zole ring are oriented at a dihedral angle of 69.62â (8)°. A classical intra-molecular N-Hâ¯O hydrogen bond is found in the mol-ecular structure. Moreover, one classical inter-molecular N-Hâ¯N and four non-classical C-Hâ¯O and C-Hâ¯N hydrogen bonds are also present in the crystal structure. Besides inter-molecular hydrogen bonds, the Cl atom forms an inter-molecular short contact [3.020â (2)â Å] with one of the nitro O atoms.
ABSTRACT
OBJECTIVE: To observe therapeutic effect of electroacupuncture (EA) at Jiaji (EX-B 2) combined with laser needle-knife on lumbar disc herniation. METHODS: One hundred and twenty cases of lumbar disc herniation were divided into an Jiaji EA group, a laser needle-knife group and a combination group (Jiaji EA plus laser needle-knife) according to random number table. Changes of symptoms at different stages before and after treatment were investigated with SF-MPQ cumulative scores. RESULTS: All the 115 cases completed all of the study, SF-MPQ score in the combination group was significantly lower than those in the Jiaji EA group and the laser needle-knife group (P<0. 01, P<0.05), with a significant difference at the end of treatment of 2 weeks (P<0.01) between the laser needle-knife group and the Jiaji EA group, and with no significant difference at treatment of 1 week and 3 weeks (P>0.05). The recurrence rate at a half year later in the combination group was significantly lower than those in laser needle-knife group and the Jiaji EA group (P<0.05). CONCLUSION: EA at Jiaji (EX-B 2) combined with laser needle-knife can significantly increase clinical therapeutic effect, alleviate pain of the patient and reduce recurrence.
