ABSTRACT
In this paper, we explored a modified Leslie-Gower predator-prey model incorporating a fear effect and multiple delays. We analyzed the existence and local stability of each potential equilibrium. Furthermore, we investigated the presence of periodic solutions via Hopf bifurcation bifurcated from the positive equilibrium with respect to both delays. By utilizing the normal form theory and the center manifold theorem, we investigated the direction and stability of these periodic solutions. Our theoretical findings were validated through numerical simulations, which demonstrated that the fear delay could trigger a stability shift at the positive equilibrium. Additionally, we observed that an increase in fear intensity or the presence of substitute prey reinforces the stability of the positive equilibrium.
ABSTRACT
Bacterial resistance caused by prolonged administration of the same antibiotics exacerbates the threat of bacterial infection to human health. It is essential to optimize antibiotic treatment measures. In this paper, we formulate a simplified model of conversion between sensitive and resistant bacteria. Subsequently, impulsive state feedback control is introduced to reduce bacterial resistance to a low level. The global asymptotic stability of the positive equilibrium and the orbital stability of the order-1 periodic solution are proved by the Poincaré-Bendixson Theorem and the theory of the semi-continuous dynamical system, respectively. Finally, numerical simulations are performed to validate the accuracy of the theoretical findings.
