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J Asian Nat Prod Res ; 26(4): 482-488, 2024 Apr.
Article in English | MEDLINE | ID: mdl-37610136

ABSTRACT

Two new guaiane-type sesquiterpenes, wenyujinolides A (1) and B (2), were isolated from the ethanol extract of Curcuma wenyujin, together with 10 known compounds. Their structures were established by extensive spectroscopic methods (IR, ESIMS, HRESIMS, ECD, 1D and 2D NMR) and comparison of their NMR data with literatures. Compounds 1 and 2 were evaluated for the inhibition of NO production in LPS induced RAW 264.7 macrophages.


Subject(s)
Curcuma , Sesquiterpenes , Curcuma/chemistry , Molecular Structure , Nitric Oxide , Lipopolysaccharides/pharmacology , Sesquiterpenes/pharmacology , Sesquiterpenes/chemistry , Sesquiterpenes, Guaiane/chemistry
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