Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 9 de 9
Filter
Add more filters










Database
Language
Publication year range
1.
JACC Case Rep ; 4(15): 941-944, 2022 Aug 03.
Article in English | MEDLINE | ID: mdl-35935163

ABSTRACT

We present a 6-year-old female child, with prenatal diagnosis of trisomy 13 mosaicism and nondisjunction, a bicuspid aortic valve, and severe aortic root dilatation. This patient is only the third reported case of aortic dilatation in the setting of trisomy 13 mosaicism. (Level of Difficulty: Intermediate.).

2.
JACC Case Rep ; 3(9): 1216-1220, 2021 Aug 04.
Article in English | MEDLINE | ID: mdl-34401763

ABSTRACT

Pulmonary artery thrombosis is reported in neonates with risk factors for hypercoagulability. No consensus exists regarding standard therapy for this condition. We present a neonate, with no risk factors for thrombosis, who was admitted after birth to the Pediatric Cardiac Intensive Care Unit with an occlusive left pulmonary artery thrombus. (Level of Difficulty: Intermediate.).

4.
Catheter Cardiovasc Interv ; 82(4): 519-25, 2013 Oct 01.
Article in English | MEDLINE | ID: mdl-23704074

ABSTRACT

OBJECTIVE: To describe patent ductus arteriosus (PDA) stenting regardless of ductal morphology in high risk patients with hypoplast physiology undergoing hybrid stage I palliation (PDA stenting and placement of bilateral pulmonary artery bands). BACKGROUND: Hybrid palliation is an accepted alternative for patients with hypoplastic left heart syndrome. Patients weighing less than 2.5 kg, history of prematurity, intracranial hemorrhage, and chromosomal abnormality belong to a high-risk group who otherwise might not be ideal candidates for traditional surgical repair (Norwood Operation). METHODS: Between May 2005 and February 2013, a series of 13 high-risk patients with hypoplast physiology with varying types of ductal morphology underwent PDA stenting as part of hybrid stage I palliation. RESULTS: Three major types of ductal morphology were identified: (1) short and semi horizontal, (2) long and semi horizontal, and (3) tortuous. All patients underwent successful PDA stenting. One patient developed proximal coarctation from inadequate coverage of the pulmonary end of the PDA and was successfully treated with a balloon expandable stent 69 days after the initial procedure. CONCLUSIONS: Mid- to long-term follow-up indicates that PDA stents remain widely patent regardless of ductal morphology until comprehensive stage II repair.


Subject(s)
Cardiac Catheterization/instrumentation , Ductus Arteriosus, Patent/therapy , Hypoplastic Left Heart Syndrome/therapy , Stents , Cardiac Catheterization/adverse effects , Combined Modality Therapy , Ductus Arteriosus, Patent/diagnosis , Female , Humans , Hypoplastic Left Heart Syndrome/diagnosis , Infant, Newborn , Ligation , Male , Palliative Care , Pulmonary Artery/surgery , Retrospective Studies , Risk Factors , Treatment Outcome
5.
Pediatr Cardiol ; 34(1): 185-8, 2013 Jan.
Article in English | MEDLINE | ID: mdl-22466622

ABSTRACT

A patient with unbalanced right ventricular dominant atrioventricular septal defect with ascending and transverse arch hypoplasia underwent hybrid stage 1 palliation. On postoperative day 7, he experienced irritability and acute cyanosis. Echocardiography demonstrated a thrombus occluding the right pulmonary artery band. Emergency cardiac catheterization confirmed thrombosis of the right pulmonary artery at the site of the band. Direct infusion of tissue plasminogen activator successfully lysed the thrombus.


Subject(s)
Palliative Care/methods , Postoperative Complications/drug therapy , Pulmonary Artery/surgery , Thrombosis/drug therapy , Tissue Plasminogen Activator/therapeutic use , Cardiac Catheterization , Child , Echocardiography , Humans , Male , Pulmonary Artery/abnormalities , Pulmonary Artery/diagnostic imaging , Thrombosis/etiology , Tissue Plasminogen Activator/administration & dosage , Treatment Outcome
6.
Ann Thorac Surg ; 94(5): 1714-6, 2012 Nov.
Article in English | MEDLINE | ID: mdl-23098950

ABSTRACT

Traumatic ventricular septal defect is an uncommon complication of blunt chest trauma. We report a case of ventricular septal avulsion, associated with traumatic ventricular septal defect and the associated management concerns.


Subject(s)
Heart Injuries/etiology , Heart Injuries/surgery , Ventricular Septum/injuries , Ventricular Septum/surgery , Wounds, Nonpenetrating/complications , Wounds, Nonpenetrating/surgery , Adolescent , Humans , Male
8.
Pediatr Infect Dis J ; 28(10): 922-5, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19738506

ABSTRACT

A 9-year-old white male with congenital aortic and subaortic stenosis palliated by the Ross-Konno procedure presented with culture-negative endocarditis. Serologic studies and polymerase chain reaction testing of resected homograft valvular tissue provided evidence of Bartonella henselae as the etiology. B. henselae can cause endocarditis in children, particularly those with underlying valvular disease. Serologic testing for B. henselae should be considered in children with culture-negative endocarditis.


Subject(s)
Angiomatosis, Bacillary/diagnosis , Aortic Valve Stenosis/complications , Bartonella henselae/isolation & purification , Endocarditis, Bacterial/diagnosis , Heart Defects, Congenital/complications , Angiomatosis, Bacillary/microbiology , Antibodies, Bacterial/blood , Aortic Valve Stenosis/surgery , Child , DNA, Bacterial/genetics , Endocarditis, Bacterial/microbiology , Heart Defects, Congenital/surgery , Humans , Male , Polymerase Chain Reaction , Serologic Tests
9.
Am J Physiol Regul Integr Comp Physiol ; 283(4): R964-71, 2002 Oct.
Article in English | MEDLINE | ID: mdl-12228067

ABSTRACT

Antagonists to the N-methyl-D-aspartate (NMDA) receptor bind to various extraneuronal tissues. We therefore assessed the expression of the main NMDA subunit, NR1, in various tissues. We demonstrate that NR1 appears to be most abundant in the rat kidney and heart. NR1 is present in total rat kidney, cortex, and medulla. Of the NR2 subunits, only the NR2C subunit protein is present in the kidney. The abundance of the NR1 subunit protein increases with kidney development. Both NR1 and NR2C are present in opossum kidney, Madin-Darby canine kidney, and LLC-PK(1) cells. Immunohistochemistry studies show that the NR1 subunit is present in the renal proximal tubule. NR1 is abundant in the atrium and ventricle but is also expressed in the aorta and pulmonary artery. The NR2 subunits are not expressed in the heart. NR1 subunit protein expression is constant throughout heart development. Finally, the NR1 subunit protein is expressed in heart cells (H9c2) grown in culture. These studies reveal the presence of the NMDA receptor in the kidney and the cardiovascular system.


Subject(s)
Aging/metabolism , Cardiovascular System/metabolism , Kidney/metabolism , Receptors, N-Methyl-D-Aspartate/metabolism , Animals , Brain/metabolism , Cells, Cultured , Dogs , Female , Immunohistochemistry , Kidney/cytology , LLC-PK1 Cells , Myocardium/cytology , Myocardium/metabolism , Opossums , Protein Isoforms/metabolism , Rats , Rats, Sprague-Dawley , Swine
SELECTION OF CITATIONS
SEARCH DETAIL
...