1.
Chem Commun (Camb)
; 50(9): 1077-9, 2014 Feb 04.
Article
in English
| MEDLINE
| ID: mdl-24310244
ABSTRACT
Boron trihalide-promoted ring-opening reactions of gem-difluorocyclopropyl ketones to give the corresponding ß-trifluoromethyl ketones and ß-halodifluoromethyl ketones were described. It was found that boron trihalides act as both Lewis acids and nucleophiles and the proximal bond prefers to cleave in this transformation.
Subject(s)
Boron/chemistry , Halogens/chemistry , Ketones/chemistry , Catalysis , Stereoisomerism
2.
Chem Commun (Camb)
; 49(84): 9833-5, 2013 Oct 28.
Article
in English
| MEDLINE
| ID: mdl-24030730
ABSTRACT
The CF3SO3H-promoted ring opening of gem-difluorocyclopropyl ketones prefers to undergo proximal bond cleavage and the subsequent cyclization with nitriles occurred smoothly to give 2-fluoropyrroles.
