1.
Mar Drugs
; 12(6): 3371-80, 2014 Jun 03.
Article
in English
| MEDLINE
| ID: mdl-24897385
ABSTRACT
Four new cembrane-type diterpenes; numerosol A-D (1-4); along with a known steroid; gibberoketosterol (5); were isolated from the Taiwanese soft coral Sinularia numerosa. The structures of these metabolites were determined by extensive analysis of spectroscopic data. Gibberoketosterol (5) exhibited cytotoxicity against P-388 (mouse lymphocytic leukemia) cell line with an ED50 of 6.9 µM.