GHz repetition rate, sub-100-fs Ho:CALGO laser at 2.1†µm with watt-level average power.

We report on a GHz fundamental repetition rate Kerr-lens mode-locked Ho:CALGO laser emitting at 2.1 µm. The laser employs a ring cavity to increase the fundamental repetition rate to 1.179 GHz and can be made to oscillate in both directions stably with nearly identical performance: for the counterclockwise oscillation, it generates 93-fs pulses at 1.68 W of average power, whereas 92 fs and 1.69 W were measured for the clockwise operation. Our current results represent the highest average power from a 2-µm GHz oscillator and, to our knowledge, the first sub-100-fs pulse duration from a Ho-based oscillator.

Repetitive transcranial magnetic stimulation alleviates glial activation through suppressing HMGB1/TLR4 pathway in a rat model of Parkinson's disease.

BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) has been demonstrated to be effective in Parkinson's disease (PD), but whether rTMS treatment has a relieving effect on neuroinflammation remains to be investigated. In this article, we explored the effects of rTMS on forelimb use asymmetry and neuroinflammation-related mechanisms in a 6-hydroxydopamine (6-OHDA)-induced PD rat model. METHODS AND RESULTS: Rats in the 6-OHDA+rTMS group received 10 Hz rTMS daily for 4 weeks. Behavioral tests (the cylinder test) were performed at the 3rd and 7th weeks after the operation. Astrocyte and microglia activation and protein levels of tyrosine hydroxylase(TH), high-mobility group box 1(HMGB1) and toll-like receptors 4(TLR4) were investigated by immunohistochemistry and Western blot analyses, respectively. After 4 weeks of treatment, forelimb use asymmetry was ameliorated in the 6-OHDA+rTMS group. Consistent with the behavioral tests, rTMS increased TH in the substantia nigra (SN) and the striatum of PD rats. High glial activation and HMGB1/TLR4 expression in the SN and the striatum were observed in the 6-OHDA group, while rTMS alleviated these changes. CONCLUSIONS: This study showed that rTMS might be a promising method for alleviating neuroinflammation in PD rat models, and the effects might be mediated through the downregulation of the HMGB1/TLR4 pathway.

Low-noise, 2-W average power, 112-fs Kerr-lens mode-locked Ho:CALGO laser at 2.1†µm.

We report on an in-band pumped soft-aperture Kerr-lens mode-locked Ho3+-doped CaGdAlO4 (Ho:CALGO) bulk laser at 2.1 µm, generating 2 W of average power with 112 fs pulses at 91-MHz repetition rate. To the best of our knowledge, this is the highest average power from a 100-fs class mode-locked laser based on a Tm3+ or Ho3+ doped bulk material. We show that the laser has excellent noise properties, with an integrated relative intensity noise of 0.02% and a timing jitter of 950 fs (rms phase noise 0.543 mrad) in the integration interval from 10 Hz to 10 MHz of offset frequency. The demonstrated combination of high average power, short pulses, and low noise makes this an outstanding laser source for many applications at 2.1 µm.

8.7-W average power, in-band pumped femtosecond Ho:CALGO laser at 2.1 µm.

We report on an in-band pumped SESAM mode-locked Ho:CALGO bulk laser with a record-high average power of 8.7 W and an optical-to-optical efficiency of 38.2% at a central wavelength of 2.1 µm. At this power level, the bulk laser generates pulses with a duration of 369 fs at an 84.4-MHz repetition rate, corresponding to a pulse energy of 103 nJ and a peak power of 246 kW. To the best of our knowledge, this is the highest average power and pulse energy directly generated from a mode-locked bulk laser in the 2-3 µm wavelength region. Our current results indicate that Ho:CALGO is a competitive candidate for average power scaling of 2-µm femtosecond lasers.

Tb,Y:SrF2 crystal for efficient laser operation in the visible spectral region.

A Tb,Y:SrF2 crystal with high optical quality is grown using the temperature gradient technique. The spectroscopic and laser properties of the crystal in the visible spectral region are studied. A fluorescence lifetime of 5.6 ms is measured from the crystal, which is beneficial for laser operation with a low threshold. A continuous-wave Tb,Y:SrF2 laser delivers an output power of 259 mW at 545 nm, with a slope efficiency of 35.2%. To the best of the authors' knowledge, this is the first report on a Tb-doped SrF2 laser and represents the highest output power for visible alkaline-earth fluoride lasers. The limitations for power scaling are discussed.

Efficient diode-pumped Er:YAP master-oscillator power-amplifier system for laser power improvement at 2920†nm.

We report on the first demonstration of laser-diode-pumped master-oscillator power-amplifier (MOPA) system based on Er-doped bulk material working at 2920 nm. The relaxation oscillation at the beginning of the laser pulse from the Er:YAlO3 (YAP) oscillator was suppressed effectively when the pump frequency was increased to 140 Hz, as a result of the establishment of a three-level system. In the amplifier, the small signal gain of the Er:YAP strongly depends on pump duration and repetition frequency, and can reach the upper limit of parasitic oscillation. Further, 25.5 mJ of output pulse energy has been achieved from the amplifier at 150 Hz frequency (2.2 ms pump duration), with over 32% of optical-to-optical efficiency. Further improvement of the amplification ability of the MOPA system was discussed.

Highly efficient Er:YAP laser with 6.9 W of output power at 2920†nm.

We report on the efficient high-power operation of a laser-diode-pumped Er3+-doped yttrium aluminum perovskite (Er:YAP) laser in the 3 µm spectral region at room temperature. 6.9 W of continuous-wave (CW) output power was obtained at 2920 nm. The slope efficiency was as high as 30.6% with respect to the absorbed pump power, which is close to the quantum defect limit (33.4%). To the best of our knowledge, this is the highest CW output power generated from 3 µm Er3+-doped solid state lasers at room temperature. Furthermore, our analysis has shown that more than 10 W of output power based on Er:YAP is possible by further mitigating the thermal lens effect.

Gain-switched laser diode seeded TDFA with 409 W picosecond pulses and 142 W spectrally flat supercontinuum output.

We report on a high-power picosecond all-fiber Tm-doped fiber amplifier (TDFA) seeded by a gain-switched laser diode (LD) in the 2 µm spectral range. A total average output power of 409 W (304 ps) has been generated at 320 MHz of repetition rate with 10 dB bandwidth of ~48 nm centered at 1970 nm. Over 140 W of spectrally flat supercontinuum (SC) output has been produced at 40 MHz of repetition rate with optimized fiber length. The 10 dB spectral bandwidth was 615 nm, ranging from 1965 to 2580 nm. The prospects for further power scaling of LD seeded ~2 µm picosecond all-fiber sources are discussed.

High-performance Ho:YAG single-crystal fiber laser in-band pumped by a Tm-doped all-fiber laser.

We report on, to the best of our knowledge, the first Q-switched single-crystal fiber (Ho:YAG SCF) laser in the 2 µm spectral range, in-band pumped by a Tm-doped all-fiber laser. A continuous-wave laser with 12.5 W output power and Q-switched laser with 1.44 mJ pulse energy and 7.5 ns pulse duration at a repetition rate of 1 kHz were demonstrated. The high laser performance is attributed to the high gain, suppressed nonlinear effects, and easy thermal management which benefited from the unique geometric construction of the SCF.

790 W incoherent beam combination of a Tm-doped fiber laser at 1941 nm using a 3 × 1 signal combiner.

In this paper, we report on a high-power incoherent beam combination of three Tm-doped fiber amplifiers at 1941 nm based on a 3×1 signal combiner. An output power of 790 W is achieved from the signal combiner with a slope efficiency of 52.2% with respect to the launched pump power and a beam quality factor M2 of 2.7. The beam quality factor is close to the theoretical limit of the 3×1 fiber combiner. The parameters of the amplifier are optimized to increase the laser efficiency. Our analyses show that this structure is sufficient to support kilowatt-level output power while maintaining the high beam quality.

High-power nanosecond pulse generation from an integrated Tm-Ho fiber MOPA over 2.1 µm.

In this paper, we report on high-power stable nanosecond pulse generation at ~2.1 µm from an integrated Tm-Ho all-fiber master oscillator power amplifier (MOPA) system. A total output power of 128.5 W is generated from the Tm-Ho hybrid MOPA, with an average power of 99.1 W from Ho emission at 2116 nm; the corresponding pulse repetition frequency and pulse width are 161 kHz and 322 ns, respectively, leading to a peak power of 1.91 kW. The Tm-Ho integrated master oscillator is designed to operate at 1980 and 2116 nm, where the former wavelength serves as the pump of the Ho-doped fiber. Stable laser pulses are generated from both the Tm and Ho oscillators owing to mutual modulation of emission from the two lasers. The prospects for further scaling in output power at ~2.1 µm using Tm-Ho integrated MOPA system are discussed.

Wavelength- and OAM-tunable vortex laser with a reflective volume Bragg grating.

Vortex beams carrying orbital angular momentum (OAM) have been recently investigated intensely in optical communication systems, as using OAM mode multiplexing simultaneously with other conventional multiplexing techniques is the key to further expand data capacity. This article demonstrates a wavelength- and OAM-tunable vortex laser at 1.6 µm in an Er:YAG system. For the first time to the best of our knowledge, a reflective volume Bragg grating (VBG) was theoretically and experimentally proved to be an effective OAM-preserving wavelength selector inside the laser cavity. A z-shaped laser cavity employing a VBG as a folding mirror was constructed for the direct generation of vortex beams, and we finally obtained wavelength-tunable beams of five OAM states (0, ± h, and ± 2h) with a narrow bandwidth less than 0.04 nm. This laser supplies a new way for optical communication by combining the spatial degree of freedom for multiplexing information channels with the conventionally used wavelength domains in packable and robust resonant cavity.

Highly efficient Tm:CaYAlO4 laser in-band pumped by a Raman fiber laser at 1.7 µm.

This paper discusses the high power, efficient operation of a Tm:CaYAlO4 (Tm:CYA) laser in-band pumped by a Raman fiber laser at 1.7 µm. We have investigated and compared laser characteristics of 4.0 at. % and 6.0 at. % doped Tm:CYA samples with both a-cut and c-cut configurations. Up to 6.8 W of output power has been generated at 1968.3 nm using a 6.0 at. % doped and a-cut Tm:CYA crystal, corresponding to a slope efficiency with respect to incident pump power of 52.3%. Laser output from both a- and c-cut samples are nearly linearly polarized with the polarization extinction ratio (PER) reaching 24 dB for the a-cut sample.

High-average-power operation of a pulsed Raman fiber amplifier at 1686 nm.

We report on high-average-power operation of a pulsed Raman fiber amplifier at ~1686 nm which cannot be covered by rare-earth-doped fiber lasers. The Raman fiber amplifier was pumped by a home-made 1565.2 nm Q-switched Er,Yb fiber laser and worked at a repetition frequency of 184 kHz. With 0.8 km Raman fiber, 4.4 W of average output power at the 1st order Stokes wavelength of 1686.5 nm was obtained for launched pump power of 16.2 W, corresponding to an optical-to-optical conversion efficiency of 27.2%. Further increasing the pump power, high-order Stokes waves grew gradually, resulting in a total output power of 6.7 W at the 19.2 W launched pump power.

Volume Bragg grating narrowed high-power and highly efficient cladding-pumped Raman fiber laser.

High-power and highly efficient operation of a single-mode cladding-pumped Raman fiber laser with narrow lasing bandwidth is demonstrated. The spectral narrowing was realized by an external cavity containing a volume Bragg grating with a center wavelength of 1658 nm. A maximum output power of 10.4 W at 1658.3 nm with a spectral linewidth (FWHM) of ∼0.1 nm was obtained for the launched pump power of 18.4 W, corresponding to a slope efficiency of 109% with respect to the launched pump power. Lasing characteristics of free-running operation are also evaluated and discussed.