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1.
BMC Infect Dis ; 22(1): 274, 2022 Mar 21.
Article in English | MEDLINE | ID: mdl-35313829

ABSTRACT

BACKGROUND: Motivated by the need for precise epidemic control and epidemic-resilient urban design, this study aims to reveal the joint and interactive associations between urban socioeconomic, density, connectivity, and functionality characteristics and the COVID-19 spread within a high-density city. Many studies have been made on the associations between urban characteristics and the COVID-19 spread, but there is a scarcity of such studies in the intra-city scale and as regards complex joint and interactive associations by using advanced machine learning approaches. METHODS: Differential-evolution-based association rule mining was used to investigate the joint and interactive associations between the urban characteristics and the spatiotemporal distribution of COVID-19 confirmed cases, at the neighborhood scale in Hong Kong. The associations were comparatively studied for the distribution of the cases in four waves of COVID-19 transmission: before Jun 2020 (wave 1 and 2), Jul-Oct 2020 (wave 3), and Nov 2020-Feb 2021 (wave 4), and for local and imported confirmed cases. RESULTS: The first two waves of COVID-19 were found mainly characterized by higher-socioeconomic-status (SES) imported cases. The third-wave outbreak concentrated in densely populated and usually lower-SES neighborhoods, showing a high risk of within-neighborhood virus transmissions jointly contributed by high density and unfavorable SES. Starting with a super-spread which considerably involved high-SES population, the fourth-wave outbreak showed a stronger link to cross-neighborhood transmissions driven by urban functionality. Then the outbreak diffused to lower-SES neighborhoods and interactively aggravated the within-neighborhood pandemic transmissions. Association was also found between a higher SES and a slightly longer waiting period (i.e., the period from symptom onset to diagnosis of symptomatic cases), which further indicated the potential contribution of higher-SES population to the pandemic transmission. CONCLUSIONS: The results of this study may provide references to developing precise anti-pandemic measures for specific neighborhoods and virus transmission routes. The study also highlights the essentiality of reliving co-locating overcrowdedness and unfavorable SES for developing epidemic-resilient compact cities, and the higher obligation of higher-SES population to conform anti-pandemic policies.


Subject(s)
COVID-19 , COVID-19/epidemiology , Cities/epidemiology , Cross-Sectional Studies , Humans , Residence Characteristics , Social Class
2.
Int J Health Geogr ; 20(1): 17, 2021 04 29.
Article in English | MEDLINE | ID: mdl-33926460

ABSTRACT

BACKGROUND: The urban built environment (BE) has been globally acknowledged as one of the main factors that affects the spread of infectious disease. However, the effect of the street network on coronavirus disease 2019 (COVID-19) incidence has been insufficiently studied. Severe acute respiratory syndrome coronavirus 2, which causes COVID-19, is far more transmissible than previous respiratory viruses, such as severe acute respiratory syndrome coronavirus, which highlights the role of the spatial configuration of street network in COVID-19 spread, as it is where humans have contact with each other, especially in high-density areas. To fill this research gap, this study utilized space syntax theory and investigated the effect of the urban BE on the spatial diffusion of COVID-19 cases in Hong Kong. METHOD: This study collected a comprehensive dataset including a total of 3815 confirmed cases and corresponding locations from January 18 to October 5, 2020. Based on the space syntax theory, six space syntax measures were selected as quantitative indicators for the urban BE. A linear regression model and Geographically Weighted Regression model were then applied to explore the underlying relationships between COVID-19 cases and the urban BE. In addition, we have further improved the performance of GWR model considering the spatial heterogeneity and scale effects by adopting an adaptive bandwidth. RESULT: Our results indicated a strong correlation between the geographical distribution of COVID-19 cases and the urban BE. Areas with higher integration (a measure of the cognitive complexity required for a pedestrians to reach a street) and betweenness centrality values (a measure of spatial network accessibility) tend to have more confirmed cases. Further, the Geographically Weighted Regression model with adaptive bandwidth achieved the best performance in predicting the spread of COVID-19 cases. CONCLUSION: In this study, we revealed a strong positive relationship between the spatial configuration of street network and the spread of COVID-19 cases. The topology, network accessibility, and centrality of an urban area were proven to be effective for use in predicting the spread of COVID-19. The findings of this study also shed light on the underlying mechanism of the spread of COVID-19, which shows significant spatial variation and scale effects. This study contributed to current literature investigating the spread of COVID-19 cases in a local scale from the space syntax perspective, which may be beneficial for epidemic and pandemic prevention.


Subject(s)
COVID-19 , Built Environment , Hong Kong , Humans , Pandemics , SARS-CoV-2
4.
Commun Biol ; 4(1): 126, 2021 01 25.
Article in English | MEDLINE | ID: mdl-33495509

ABSTRACT

It is important to forecast the risk of COVID-19 symptom onset and thereby evaluate how effectively the city lockdown measure could reduce this risk. This study is a first comprehensive, high-resolution investigation of spatiotemporal heterogeneities on the effect of the Wuhan lockdown on the risk of COVID-19 symptom onset in all 347 Chinese cities. An extended Weight Kernel Density Estimation model was developed to predict the COVID-19 onset risk under two scenarios (i.e., with and without the Wuhan lockdown). The Wuhan lockdown, compared with the scenario without lockdown implementation, in general, delayed the arrival of the COVID-19 onset risk peak for 1-2 days and lowered risk peak values among all cities. The decrease of the onset risk attributed to the lockdown was more than 8% in over 40% of Chinese cities, and up to 21.3% in some cities. Lockdown was the most effective in areas with medium risk before lockdown.


Subject(s)
COVID-19/epidemiology , COVID-19/prevention & control , Models, Statistical , Pandemics/prevention & control , Quarantine/methods , SARS-CoV-2 , Spatial Analysis , COVID-19/virology , China/epidemiology , Cities/epidemiology , Data Accuracy , Forecasting/methods , Humans , Prognosis , Risk Factors , Transients and Migrants/statistics & numerical data
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