[Sex hormone receptors in pituitary prolactinomas].

An attempt was made to interpret the mechanism responsible for the occurrence of pituitary tumors - prolactinoma in persons of different sex. The presence or absence of androgenic receptors in the tumors was studied. Analysis of the concentration of nuclear receptors, estrogen ones in particular, showed their higher concentration in prolactin-positive pituitary adenomas than in inactive pituitary adenomas. Androgen receptors were detected in the gonadotropic and lactotropic cells of the Intact pituitary. Analysis of the concentration of nuclear testosterone receptors in different morphological types of pituitary adenomas revealed no differences in the luteinizing hormone/follicle-stimulating hormone-positive and prolactin-positive tumors.