ABSTRACT
OBJECTIVE: In this study, we evaluated the effect of low-level lasers on the healing of tympanic membrane perforation, one of the most common otological pathologies. METHODS AND MATERIALS: Twenty-four guinea pigs were randomly assigned to either the experimental or control group. One day after the induction of a 2 mm diameter, centred myringotomy in all animals, the tympanic membranes in the experimental group were irradiated with 630 and 860 nm lasers for 10 days. Two weeks later, histological changes in the membranes were evaluated. RESULTS: Tympanic membrane thickening and inflammatory cell infiltration in the tympanic membranes and surrounding tissues were significantly less in the experimental group (p < 0.001). The distance from the external auditory canal wall to the malleus tip did not differ significantly between the two groups (p = 0.42). CONCLUSION: The results show that the combined application of 630 and 860 nm lasers had a significant effect on the healing of tympanic membrane perforation, and on the prevention of thick fibrotic or atelectatic neomembrane formation.
Subject(s)
Low-Level Light Therapy/methods , Tympanic Membrane Perforation/radiotherapy , Wound Healing/physiology , Animals , Guinea Pigs , Male , Prospective Studies , Treatment Outcome , Tympanic Membrane/radiation effectsABSTRACT
AIM: Abdominal complications following open heart surgery remain rare but fatal events with mortality rates of 14.5% up to 100%. Manifestations and managements of these complications are varying. Approximately, 25% of patients with gastrointestinal complications require surgical management with obviously higher mortality risks. The aim of this study was to determine the perioperative prognostic factors of gastrointestinal complications with surgical consequences after cardiac surgery. METHODS: The study enrolled 15.737 patients who underwent open heart surgery between January 2002 and September 2007. Sixteen (0.1%) persons required laparatomy due to postoperative gastrointestinal complications. Additionally, the preoperative, operative, and postoperative risk factors for this condition were studied. RESULTS: Among the patients enrolled, 15.737 patients underwent open heart surgery while 16 (0.1%) required laparatomy procedures due to gastrointestinal complications. They were comprised of 11 (68.8%) men and 5 (31.3%) women at a mean age of 62.88±12.56 years. There was a history of hypertension in 9 (56.3%) patients, hypercholesterolemia in 11 (68.8%), renal failure in 4 (25%), previous CABG in 2 (12.5%) and PTCA in 2 (12.5%). Morbidity and mortality were significantly higher in this group of patients with a mortality rate of 68.8% (68.8% versus 1.6%). CONCLUSION: Our multivariate logistic regression model identified the following parameters to be the prognostic factors for gastrointestinal complications with surgical consequences: a history of previous CABG, previous PTCA, preoperative renal failure, preoperative anticoagulant agent use, valve surgery, combined valve and CABG surgery, and intra-aortic balloon pump requirement with OR of 51.95, 4.623, 26.436, 0.140, 5.43, 11.469 and 3.76, respectively.
Subject(s)
Cardiac Surgical Procedures/adverse effects , Gastrointestinal Diseases/surgery , Laparotomy , Aged , Cardiac Surgical Procedures/mortality , Cross-Sectional Studies , Female , Gastrointestinal Diseases/etiology , Gastrointestinal Diseases/mortality , Humans , Iran , Laparotomy/adverse effects , Laparotomy/mortality , Logistic Models , Male , Middle Aged , Odds Ratio , Risk Assessment , Risk Factors , Treatment OutcomeSubject(s)
Chylothorax/etiology , Coronary Artery Bypass/adverse effects , Mammary Arteries/transplantation , Tissue and Organ Harvesting/adverse effects , Chylothorax/diagnosis , Chylothorax/diet therapy , Coronary Artery Bypass/methods , Diet, Fat-Restricted , Electrocoagulation , Humans , Lymph Nodes/injuries , Male , Mediastinum , Middle Aged , Rare Diseases , Tissue and Organ Harvesting/methodsABSTRACT
Vascular Behcet's disease has a poor prognosis. This poor prognosis is due to postoperative complications including pseudoaneurysm with 50% occurrence after previous surgical repair of aneurysm especially at the site of surgery. It is suggested that the fragility of the vascular wall may play a major role in this recurrence. Recent studies have demonstrated the effectiveness of endovascular stent-grafting for recurrent aortic aneurysm in patients with Behcet's disease. We present a recurrent aneurysm of the abdominal aorta at a previously scarred operative site in a known case of Behcet's disease. We attempted an endovascular treatment.
Subject(s)
Aneurysm, False/surgery , Aortic Aneurysm, Abdominal/surgery , Behcet Syndrome/complications , Blood Vessel Prosthesis Implantation/adverse effects , Adult , Aneurysm, False/diagnostic imaging , Aneurysm, False/etiology , Angiography, Digital Subtraction , Aortic Aneurysm, Abdominal/diagnostic imaging , Aortic Aneurysm, Abdominal/etiology , Aortography/methods , Behcet Syndrome/diagnostic imaging , Behcet Syndrome/surgery , Blood Vessel Prosthesis , Blood Vessel Prosthesis Implantation/instrumentation , Humans , Male , Recurrence , Reoperation , Stents , Treatment OutcomeABSTRACT
AIM: The intra-aortic balloon pump (IABP) is commonly used for decreasing myocardial oxygen demand by systolic unloading in perioperative heart failure. The aim of this study was to determine perioperative prognostic factors for in-hospital mortality in coronary artery bypass grafting patients who received the intraaortic balloon pump. METHODS: A total of 271 patients who underwent coronary artery bypass grafting and received intra-aortic balloon pump perioperatively between January 2002 and September 2006 were studied. The preoperative, operative and postoperative risk factors for early death were evaluated. RESULTS: Early mortality rate in the study population was 17.3%. From variables entered into multivariate logistic regression the following parameters were identified as prognostic factors for early death: left main disease, diabetes, postoperative renal failure and cardiac arrest (P<0.05). The minor and major intra-aortic balloon pump related complications were not significant in univariate and multivariate analysis and its rate was 3.6%. CONCLUSION: According to our study the mortality of IABP group is low compared to other studies, as well as IABP-associated complications. Also it revealed that there is no correlation between IABP-associated complications and early mortality.
