1.
Eur J Med Res
; 26(1): 74, 2021 Jul 13.
Article
in English
| MEDLINE
| ID: mdl-34256825
ABSTRACT
BACKGROUND: Acquired reactive perforating collagenosis (ARPC) is a rare form of transepithelial elimination in which altered collagen is extruded through the epidermis. CASE PRESENTATION: A 23-year-old male presented with cup-like ulcerated lesions on his limbs since 3 months. A series of serological and immunological tests showed no abnormalities. A diagnosis of ARPC was based on skin biopsy findings. The patient was cured using treatment with itraconazole for 8 weeks, in the absence of a fungal infection. CONCLUSIONS: The anti-inflammatory and anti-angiogenic effects of itraconazole can have good therapeutic benefits for ARPC.
Subject(s)
Antifungal Agents/therapeutic use , Collagen Diseases/drug therapy , Itraconazole/therapeutic use , Skin Diseases/drug therapy , Adult , Collagen Diseases/pathology , Humans , Male , Prognosis , Skin Diseases/pathology , Young Adult
2.
Dermatol Ther
; 33(1): e13149, 2020 01.
Article
in English
| MEDLINE
| ID: mdl-31670862