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World J Gastroenterol ; 13(45): 6115-8, 2007 Dec 07.
Article in English | MEDLINE | ID: mdl-18023113

ABSTRACT

We report a 55-year-old male who developed advanced hepatic metastasis and peritoneal carcinomatosis after resection of remnant gastric cancer resection 3 mo ago. The patient only received epidermal growth factor (EGF) receptor antibody (Cetuximab) plus recombinant human endostatin (Endostar). Anti-tumor activity was assessed by (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computer tomography (PET/CT) at baseline and then every 4 wk. The case illustrates that (18)FDG-PET/CT could make an early prediction of the response to Cetuximab plus Endostar in such clinical situations. (18)FDG-PET/CT is a useful molecular imaging modality to evaluate the biological response advanced hepatic metastasis and peritoneal carcinomatosis to Cetuximab plus Endostar in patients after remnant gastric cancer resection.


Subject(s)
Adenocarcinoma/drug therapy , Antibodies, Monoclonal/therapeutic use , Antineoplastic Agents/therapeutic use , Endostatins/therapeutic use , Liver Neoplasms/drug therapy , Stomach Neoplasms/pathology , Adenocarcinoma/secondary , Adenocarcinoma/surgery , Antibodies, Monoclonal, Humanized , Cetuximab , Fluorodeoxyglucose F18 , Humans , Liver Neoplasms/secondary , Male , Middle Aged , Positron-Emission Tomography , Recombinant Proteins , Stomach Neoplasms/surgery
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