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1.
Rev Sci Instrum ; 91(7): 073505, 2020 Jul 01.
Article in English | MEDLINE | ID: mdl-32752858

ABSTRACT

A Multi-Color (MC) gas puff imaging diagnostic has been developed on HL-2A tokamak. This diagnostic can simultaneously measure two-dimensional (2D, radial, and poloidal) electron density and temperature distributions with a good spatial resolution of 2.5 × 2.5 mm2 and a temporal resolution of about 100 µs at best in edge plasmas. The 2D electron density and temperature distributions are inferred from the ratios of intensities of three different neutral helium emission lines; therefore, it is also referred to as helium beam probe or beam emission spectroscopy on thermal helium. A compact light splitter is used to split the inlet visible emission beam into four channels, and the specific neutral helium lines of the wavelengths λ1 = 587.6 nm, λ2 = 667.8 nm, λ3 = 706.5 nm, and λ4 = 728.1 nm are measured, respectively. This MC diagnostic has been experimentally tested and calibrated on a linear magnetic confinement device Peking University Plasma Test device, and the measured 2D electron density and temperature distributions are compared with the Langmuir probe measurements.

2.
Article in Chinese | MEDLINE | ID: mdl-31550770

ABSTRACT

The number of patients with allergic rhinitis (AR) have been increasing in the world. Establishment of AR model in mice is an important method for the study of this disease. However, there is still no consensus standard for the modeling methods, selection of allergens and adjuvants, and evaluation parameter of AR modeling. Here, we introduce the advancement of AR mouse model in recent years from the above, and provide evidence of references for the standardized process of AR mouse model establishment.


Subject(s)
Disease Models, Animal , Rhinitis, Allergic , Adjuvants, Immunologic , Animals , Humans , Mice
3.
Rev Sci Instrum ; 89(10): 10F112, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30399885

ABSTRACT

Newly developed large-area pixelated two-dimensional detector and two-crystal assemblies were deployed for the first time on tokamaks to enable time-resolved Bragg-diffracted x-ray imaging with good framing rate and water-cooling capabilities for in-vacuum long-pulse operations. High-quality helium-like (He-like) and hydrogen-like (H-like) argon spectra have been observed simultaneously for the first time on a single detector for a wide range of plasma parameters to infer both ion temperature and rotation profiles and support studies on spontaneous rotation, impurity transport, and RF physics. Since tokamak plasmas rotate in both the poloidal (θ) and toroidal (ϕ) directions, a reliable wavelength calibration is needed to account for the correct Doppler shift as well as to compute the spectrometer's instrumental function. Lyα lines emitted from Cd x-ray tubes are proposed to be used as "markers" to provide an in situ calibration of the EAST's X-ray imaging crystal spectrometer systems measuring He- and H-like argon spectra. The first lab test indicated that the X-ray tube can excite strong Lyα lines at 15 kV voltage and 1 mA current when the crystal is shined for 10 min. Other indirect calibration methods using locked-mode discharge scenarios were also studied as complementary methods.

4.
Rev Sci Instrum ; 89(10): 10F110, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30399886

ABSTRACT

A two-crystal X-ray spectrometer system has been implemented in the EAST tokamak to simultaneously diagnose high- and low-temperature plasmas using He- and H-like argon spectra. But for future fusion devices like ITER and Chinese Fusion Engineering Test Reactor (CFETR), argon ions become fully stripped in the core and the intensity of the H-like lines will be significantly at high temperatures (Te > 5 keV). With increasing auxiliary heating power on EAST, the core plasma temperature could also reach 5 keV and higher. In such conditions, the use of a xenon puff becomes an appropriate choice for both ion-temperature and flow-velocity measurements. A new two-crystal system using a quartz 110 crystal (2d = 4.913 Å) to view He-like argon lines and a quartz 011 crystal (2d = 6.686 Å) to view Ne-like xenon spectra has been deployed on a poloidal X-ray crystal spectrometer. While the He-like argon spectra will be used to measure the plasma temperature in the edge plasma region, the Ne-like xenon spectra will be used for measurement in the hot core. The new crystal arrangement allows a wide temperature measurement ranging from 0.5 to 10 keV or even higher, being the first tests for burning plasmas like ITER and CFETR. The preliminary result of lab-tests, Ne-like xenon lines measurement will be presented.

5.
Rev Sci Instrum ; 89(10): 10D119, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30399940

ABSTRACT

The core toroidal charge exchange recombination spectroscopy system on experimental advanced superconducting tokamak (EAST) has been enhanced recently to extend the spectral range. The C VI charge exchange line at 529.059 nm, Ne X line at 524.897 nm, and Li III line at 516.67 nm are observed successfully. The measurements were performed by injecting neon gas and dropping lithium powder simultaneously during the 2016 EAST experimental campaign. One channel connected to a neon lamp is used to perform the real-time wavelength calibration on a shot-to-shot basis. The preliminary results indicate that ion temperature profiles from the carbon and neon impurities are in excellent agreement and provide a consistency check of the measurement from different impurities. Toroidal velocity correction associated with the energy-dependent cross section has been performed. Toroidal rotation of neon impurity is obviously faster than C VI across the whole profile. A cumulative and saturated effect of core lithium ions was observed.

6.
Rev Sci Instrum ; 89(7): 073503, 2018 Jul.
Article in English | MEDLINE | ID: mdl-30068091

ABSTRACT

Neutral beam attenuation is simulated by means of consulting the ADAS (Atomic Data and Analysis Structure) database based on experimentally diagnosed radial plasma density and electron temperature profiles on the Experimental Advanced Superconducting Tokamak (EAST). Two-dimensional distributions of beam emission and charge exchange recombination photon flux are simulated, taking neutral beam attenuation into account, together with comparison with experimental results of Beam Emission Spectroscopy (BES) and Charge eXchange Recombination Spectroscopy (CXRS). A photon number which is over 1014 promises a sufficient photon flux for typical detectors of BES, CXRS, and UltraFast-CXRS (UF-CXRS) diagnostics. Evidence shows that the ADAS database overvalues neutral beam injection effective stopping coefficient on the EAST tokamak. The joint diagnostic of BES and UF-CXRS which is under development to measure plasma pressure with a high temporal resolution of 1 µs will have strong signals in a radial range of 0.6 < ρ < 0.8. The steep gradients of plasma density and C6+ density at ρ ∼ 1 bring great difficulty to edge plasma investigation by this joint diagnostic.

7.
Appl Radiat Isot ; 137: 123-128, 2018 Jul.
Article in English | MEDLINE | ID: mdl-29609052

ABSTRACT

The accelerator driven subcritical system (ADS) is regarded as a safe and clean nuclear power system, which can be used for the transmutation of nuclear waste and the breeding of nuclear fuel. In this study, in order to validate nuclear data and the neutron transportation performance of the materials related to ADS, we measured the leakage neutron spectra from multiple-slab sample assemblies using 14.8 MeV D-T neutrons. Two types of assemblies comprising A-1 (W+U+C+CH2) and A-2 (U+C+CH2) were both built up gradually starting with the first wall. The measured spectra were compared with those calculated using the Monte Carlo code neutron transport coed (MCNP)-4C. A comparison of the results showed that the experimental leakage neutron spectra for both A-1 or A-2 were reproduced well by the three evaluated nuclear data libraries with discrepancies of less than 15% (A-1) and 12% (A-2), except when below 3 MeV. For 2-cm and 5-cm uranium samples, the CENDL-3.1 calculations exhibited large discrepancies in the energy range of 2-8 MeV and above 13 MeV. Thus, the CENDL-3.1 library for uranium should be reevaluated, especially around this energy range. It was significant that the leakage neuron spectra changed clearly when the latest material layer was added during the building of assemblies A-1 and A-2.

8.
Rev Sci Instrum ; 88(8): 083505, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28863624

ABSTRACT

Beam Emission Spectroscopy (BES) diagnostic based on Neutron Beam Injection (NBI) on the Experimental Advanced Superconducting Tokamak has been developed. This system consists of 16 × 8 channels which can diagnose the density fluctuation in a rectangular area of about 20 × 10 cm2 in the cross section, whose radial position is adjustable from the core to edge just by means of changing the angle of the rotation mirror. The spatial resolution is about 1-3 cm according to the diagnosed radial position. The temporal resolution is 1 µs. Space calibration of the diagnostic system is done based on the reversibility of the optical path. The NBI modulation experiment shows the success of BES development.

9.
Rev Sci Instrum ; 87(11): 11E552, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27910605

ABSTRACT

In toroidal magnetic fusion devices, fast-ion D-alpha diagnostic (FIDA) is a powerful method to study the fast-ion feature. The fast-ion characteristics can be inferred from the Doppler shifted spectrum of Dα light according to charge exchange recombination process between fast ions and probe beam. Since conceptual design presented in the last HTPD conference, significant progress has been made to apply FIDA systems on the Experimental Advanced Superconducting Tokamak (EAST). Both co-current and counter-current neutral beam injectors are available, and each can deliver 2-4 MW beam power with 50-80 keV beam energy. Presently, two sets of high throughput spectrometer systems have been installed on EAST, allowing to capture passing and trapped fast-ion characteristics simultaneously, using Kaiser HoloSpec transmission grating spectrometer and Bunkoukeiki FLP-200 volume phase holographic spectrometer coupled with Princeton Instruments ProEM 1024B eXcelon and Andor DU-888 iXon3 1024 CCD camera, respectively. This paper will present the details of the hardware descriptions and experimental spectrum.

10.
Rev Sci Instrum ; 87(11): 11E539, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27910672

ABSTRACT

A Charge eXchange Recombination Spectroscopy (CXRS) diagnostic system has been developed to measure profiles of ion temperature and rotation since 2014 on EAST. Several techniques have been developed to improve the spatial calibration of the CXRS diagnostic. The sightline location was obtained by measuring the coordinates of three points on each sightline using an articulated flexible coordinate measuring arm when the vessel was accessible. After vacuum pumping, the effect of pressure change in the vacuum vessel was evaluated by observing the movement of the light spot from back-illuminated sightlines on the first wall using the newly developed articulated inspection arm. In addition, the rotation of the periscope after vacuum pumping was derived by using the Doppler shift of neutral beam emission spectra without magnetic field. Combining these techniques, improved spatial calibration was implemented to provide a complete and accurate description of the EAST CXRS system. Due to the effects of the change of air pressure, a ∼0.4° periscope rotation, yielding a ∼20 mm movement of the major radius of observation positions to the lower field side, was derived. Results of Zeeman splitting of neutral beam emission spectra with magnetic field also showed good agreement with the calibration results.

11.
Rev Sci Instrum ; 87(11): 11E501, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27910523

ABSTRACT

An edge toroidal charge exchange recombination spectroscopy (eCXRS) diagnostic, based on a heating neutral beam injection (NBI), has been deployed recently on the Experimental Advanced Superconducting Tokamak (EAST). The eCXRS, which aims to measure the plasma ion temperature and toroidal rotation velocity in the edge region simultaneously, is a complement to the exiting core CXRS (cCXRS). Two rows with 32 fiber channels each cover a radial range from ∼2.15 m to ∼2.32 m with a high spatial resolution of ∼5-7 mm. Charge exchange emission of Carbon VI CVI at 529.059 nm induced by the NBI is routinely observed, but can be tuned to any interested wavelength in the spectral range from 400 to 700 nm. Double-slit fiber bundles increase the number of channels, the fibers viewing the same radial position are binned on the CCD detector to improve the signal-to-noise ratio, enabling shorter exposure time down to 5 ms. One channel is connected to a neon lamp, which provides the real-time wavelength calibration on a shot-to-shot basis. In this paper, an overview of the eCXRS diagnostic on EAST is presented and the first results from the 2015 experimental campaign will be shown. Good agreements in ion temperature and toroidal rotation are obtained between the eCXRS and cCXRS systems.

12.
Rev Sci Instrum ; 87(11): 11E326, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27910526

ABSTRACT

A two-crystal assembly was deployed on the tangential X-ray crystal spectrometer to measure both helium-like and hydrogen-like spectra on EAST. High-quality helium-like and hydrogen-like spectra were observed simultaneously for the first time on one detector for a wide range of plasma parameters. Profiles of line-integrated core ion temperatures inferred from two spectra were consistent. Since tungsten was adopted as the upper divertor material, one tungsten line (W XLIV at 4.017 Å) on the short-wavelength side of the Lyman-α line (Lα1) was identified for typical USN discharges, which was diffracted by a He-like crystal (2d = 4.913 Å). Another possible Fe XXV line (1.85 Å) was observed to be located on the long-wavelength side of resonance line (w), which was diffracted from a H-like crystal (2d = 4.5622 Å) on the second order. Be-like argon lines were also observable that fill the detector space between the He-like and H-like spectra.

13.
Eur Rev Med Pharmacol Sci ; 19(20): 3955-60, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26531285

ABSTRACT

OBJECTIVE: To observe the one-year neurologic prognostic outcome of newborns with moderate and severe hypoxic-ischemic encephalopathy (HIE) who received recombinant human erythropoietin (rhuEPO) combined with exogenous monosialotetrahexosylganglioside (GM1) treatment to provide new guidelines for clinical treatment. PATIENTS AND METHODS: Seventy-six newborns with moderate and severe HIE were selected from February 2011 to February 2014 in our hospital. This study received the informed consent of our hospital's Ethics Committee and the newborns' guardians. The newborns were divided to an observation group (n = 34 cases) and a control group (n = 42 cases). All newborns underwent hypothermia and conventional treatment for their conditions. The control group received GMl treatment and observation group received rhuEPO combined with GMl treatment. The curative differences and neural behavior from these two groups were compared. RESULTS: The excellent, efficient proportion and total effective rate of the newborns from the observation group were higher than the control group. The death rate, cerebral palsy and the invalid ratio of the newborns from the observation group were lower than that of the control group. Awareness, muscle tension, primitive reflex and increased intracranial pressure recovery time of the newborns in the observation group were less than those of the control group. The Neonatal Behavior Neurological Assessment (NBNA) score of both groups after the treatment of 7, 14 and 28 days were significantly higher and increased with time (p < 0.05). The MDI, PDI and DQ score of newborns from the two groups all increased after treatment of 3, 6 and 12 months than those of before, which increased with time (p < 0.05). CONCLUSIONS: The rhuEPO + GMl treatment in newborns with HIE improves short-term clinical effects and long-term neurological symptoms.


Subject(s)
Erythropoietin/administration & dosage , Hypoxia-Ischemia, Brain/diagnosis , Hypoxia-Ischemia, Brain/drug therapy , Recombinant Proteins/administration & dosage , Severity of Illness Index , Sphingolipid Activator Proteins/administration & dosage , Cerebral Palsy/diagnosis , Cerebral Palsy/drug therapy , Drug Therapy, Combination , Female , Humans , Infant, Newborn , Male , Neurologic Examination/methods , Prognosis , Treatment Outcome
14.
Rev Sci Instrum ; 85(11): 11D410, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25430173

ABSTRACT

Measurement and control of the current profile is essential for high performance and steady state operation of Experimental Advanced Superconducting Tokamak (EAST). For this purpose, a conventional Motional Stark Effect (MSE) diagnostics utilizing photoelastic modulators is proposed and investigated. The pilot experiment includes one channel to verify the feasibility of MSE, whose sightline intersects with Neutral Beam Injection at major radius of R = 2.12 m. A beam splitter is adopted for simultaneous measurements of Stark multiplets and their polarization directions. A simplified simulation code was also developed to explore the Stark splitting spectra. Finally, the filter is optimized based on the viewing geometry and neutral beam parameters.

15.
Rev Sci Instrum ; 85(11): 11E406, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25430313

ABSTRACT

Upgrade of the imaging X-ray crystal spectrometers continues in order to fulfill the high-performance diagnostics requirements on EAST. For the tangential spectrometer, a new large pixelated two-dimensional detector was deployed on tokamaks for time-resolved X-ray imaging. This vacuum-compatible detector has an area of 83.8 × 325.3 mm(2), a framing rate over 150 Hz, and water-cooling capability for long-pulse discharges. To effectively extend the temperature limit, a double-crystal assembly was designed to replace the previous single crystals for He-like argon line measurement. The tangential spectrometer employed two crystal slices attached to a common substrate and part of He- and H-like Ar spectra could be recorded on the same detector when crystals were chosen to have similar Bragg angles. This setup cannot only extend the measurable Te up to 10 keV in the core region, but also extend the spatial coverage since He-like argon ions will be present in the outer plasma region. Similarly, crystal slices for He-like iron and argon spectra were adopted on the poloidal spectrometer. Wavelength calibration for absolute rotation velocity measurement will be studied using cadmium characteristic L-shell X-ray lines excited by plasma radiation. A Cd foil is placed before the crystal and can be inserted and retracted for in situ wavelength calibration. The Geant4 code was used to estimate X-ray fluorescence yield and optimize the thickness of the foil.

16.
Rev Sci Instrum ; 85(11): 11E428, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25430335

ABSTRACT

Charge eXchange Recombination Spectroscopy (CXRS) and Beam Emission Spectroscopy (BES) diagnostics based on a heating neutral beam have recently been installed on EAST to provide local measurements of ion temperature, velocity, and density. The system design features common light collection optics for CXRS and BES, background channels for the toroidal views, multi-chord viewing sightlines, and high throughput lens-based spectrometers with good signal to noise ratio for high time resolution measurements. Additionally, two spectrometers each has a tunable grating to observe any wavelength of interest are used for the CXRS and one utilizes a fixed-wavelength grating to achieve higher diffraction efficiency for the BES system. A real-time wavelength correction is implemented to achieve a high-accuracy wavelength calibration. Alignment and calibration are performed. Initial performance test results are presented.

17.
Rev Sci Instrum ; 79(10): 10F337, 2008 Oct.
Article in English | MEDLINE | ID: mdl-19044644

ABSTRACT

The stellarator Wendelstein 7-X will allow for quasicontinuous operation with the duration only being limited to two 30 min discharges per day, at a continuous heating power of 10 MW electron cyclotron resonance heating (ECRH) at 140 GHz, by the capacity of the cooling water reservoir. This will result in high thermal loads on all plasma facing components of 50-100 kW/m(2) from radiation alone and of up to about 500 kW/m(2) on components additionally exposed to convective loads. In high density scenarios toroidally varying ECRH stray radiation levels of 50-200 kW/m(2) need to be coped with, requiring careful material selection and different shielding and hardening techniques. Furthermore, a gradual buildup of coatings on plasma facing optical components, which without any measures being taken, would lead to high transmission losses already within a few days of long pulse operation (equivalent to about 1 year of operation in pulsed devices like JET or ASDEX-upgrade) and therefore needs to be prevented as much as possible. In addition in situ cleaning as well as absolute calibration techniques need to be developed for all plasma facing optical systems. Here we report about some of our efforts to find, for various types of diagnostics, ways to cope with these adverse effects. Moreover, we give a few examples for individual diagnostic specific issues with respect to quasicontinuous operation, such as the development of a special integrator for the magnetic diagnostics as well as special interferometer types which can cope with unavoidable vibrations and slow path length changes due to, e.g., thermal expansion of the plasma vessel.

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