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Mutations in influenza A virus (H5N1) and possible limited spread, Turkey, 2006.

Altiok, Ender; Taylan, Fulya; Yenen, Osman S; Demirkeser, Gülsah; Bozaci, Mürvet; Onel, Derya; Akcadag, Birsen; Iyisan, A Selma; Ciblak, Meral; Bozkaya, Emel; Yuksel, Sirin; Badur, Selim.

Emerg Infect Dis ; 14(3): 491-2, 2008 Mar.

Article in English | MEDLINE | ID: mdl-18325270

ABSTRACT

We report mutations in influenza A virus (H5N1) strains associated with 2 outbreaks in Turkey. Four novel amino acid changes (Q447L, N556K, and R46K in RNA polymerase and S133A in hemagglutinin) were detected in virus isolates from 2 siblings who died.

Subject(s)

Chickens/virology , Influenza A Virus, H5N1 Subtype/genetics , Influenza in Birds/virology , Influenza, Human/virology , Amino Acid Sequence , Animals , Disease Outbreaks , Humans , Influenza in Birds/epidemiology , Influenza, Human/epidemiology , Mutation , Turkey/epidemiology

ABSTRACT

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