1.
Hum Pathol
; 14(2): 182-4, 1983 Feb.
Article
in English
| MEDLINE
| ID: mdl-6131861
ABSTRACT
Two fatal cases of widespread necrotizing vasculitis associated with diphenylhydantoin (Dilantin) are presented. Toxic and allergic reactions associated with diphenylhydantoin therapy have been discussed and reviewed in numerous reports since the late 1930s. This vascular complication, however, has previously been reported only twice. In this report, the authors discuss similarities in their two cases and the peculiarities of this entity in the broad spectrum of necrotizing angiitides.
Subject(s)
Phenytoin/adverse effects , Polyarteritis Nodosa/chemically induced , Aged , Blood/microbiology , Bronchitis/etiology , Eosinophilia/etiology , Humans , Liver/pathology , Lymph Nodes/pathology , Male , Middle Aged , Phenytoin/therapeutic use , Polyarteritis Nodosa/complications , Portal Vein/pathology , Pulmonary Artery/pathology , Renal Artery/pathology , Seizures/drug therapy , Splenic Artery/pathology , Staphylococcus/isolation & purification
2.
Arch Surg
; 94(2): 267-70, 1967 Feb.
Article
in English
| MEDLINE
| ID: mdl-6016276