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1.
Injury ; 55(6): 111542, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38626585

ABSTRACT

INTRODUCTION: Wound irrigation has been employed as an important surgical step to remove bacteria, devitalized tissues, and foreign bodies from surgical sites to prevent infection and confer to the wound maximum potential of healing. METHOD: A prospective study was conducted at Federal Medical Centre, Gusau, between January 2019- August 2023 to assess the benefit of antibiotics as additives in irrigation of dirty wounds. Seven (7) patients in total were presented with severe cut-throat injuries that require laryngopharyngoplasty. A combination of injection ciprofloxacin and metronidazole were used as additives into 1 L of normal saline, low pressure irrigation was done using 20mls syringe fitted to a broken needle or canular. Dysphagia Outcome and Severity Scale (DOSS) was used to assess return of pharyngeal function. RESULT: The mean time of presentation of the patients was 34 ± 29 h (µ ± standard deviation) and a range of 6-72 h. The mean repair time was 58.3 ± 38.4 h with a range of 24-120 h. Most of the patients (85.7 %) had dysphagia outcome and severity scale of level 5 when per oral feeding was started with steady progress until discharge day. CONCLUSION: Wound irrigation is one of the most crucial steps in treating severe cut-throat injuries. Based on our experience, adding antibiotics to the irrigant has shown potential in the control of local infection, particularly where patients present late.


Subject(s)
Anti-Bacterial Agents , Pharynx , Therapeutic Irrigation , Humans , Therapeutic Irrigation/methods , Prospective Studies , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Male , Adult , Female , Pharynx/injuries , Middle Aged , Wound Healing , Treatment Outcome , Ciprofloxacin/therapeutic use , Ciprofloxacin/administration & dosage , Metronidazole/therapeutic use , Deglutition Disorders , Surgical Wound Infection/prevention & control , Young Adult
2.
Ecohealth ; 17(3): 393-397, 2020 09.
Article in English | MEDLINE | ID: mdl-33106981

ABSTRACT

Rift Valley fever is an arboviral zoonoses causing severe morbidity and mortality among humans and animals in many African countries. A cross-sectional study in populations of sheep reared around the Gidan-Waya Forest Reserve located in Jema'a LGA of Kaduna State, Nigeria to determine the serological evidence of exposure to Rift Valley fever virus (RVFV) using a commercial competitive enzyme-linked immunosorbent assay. Of the 200 sheep sampled, 9 (4.5%; 95 CI 2.23-8.33) were positive for antibodies to the RVFV. The detection of antibodies suggests a covert circulation among the sheep and may be indicative of a subclinical infection.


Subject(s)
Rift Valley Fever/transmission , Rift Valley fever virus/isolation & purification , Sheep Diseases/transmission , Sheep/microbiology , Animals , Antibodies, Viral/isolation & purification , Cross-Sectional Studies , Enzyme-Linked Immunosorbent Assay , Feces/microbiology , Female , Male , Nigeria , Rift Valley Fever/diagnosis
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